Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9586346 | 1.00 | PRCP (0.31) | PRCPSIGMAR1MEN1KMT2AGRIN1 | |
| SCHEMBL7200857 | 0.93 | — | — | |
| SCHEMBL8692806 | 0.91 | — | — | |
| SCHEMBL1448263 | 0.82 | SOS1 (0.33) | — | |
| SCHEMBL6024634 | 0.67 | SOS1 (0.31) | — | |
| SCHEMBL4450140 | 0.66 | — | — | |
| SCHEMBL6496554 | 0.66 | GRIN1 (0.37) | PRCPSIGMAR1MEN1KMT2AGRIN1 | |
| SCHEMBL1515302 | 0.66 | GRIN1 (0.37) | PRCPSIGMAR1MEN1KMT2AGRIN1 | |
| SCHEMBL633802 | 0.66 | GRIN1 (0.37) | PRCPSIGMAR1MEN1KMT2AGRIN1 | |
| SCHEMBL13300994 | 0.66 | GRIN1 (0.37) | PRCPSIGMAR1MEN1KMT2AGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350702-A | 2-SUBSTITUTED BENZISOTHIAZOLONES | BEECHAM GROUP LIMITED (GB) | 1982-09-21 | — | — | US | disclosed |
| US-4243669-A | ANTICOAGULANTS | BEECHAM GROUP LIMITED (GB) | 1981-01-06 | — | — | US | disclosed |
| US-4212979-A | ANTITHROMOGENIC | BEECHAM GROUP LIMITED (GB) | 1980-07-15 | — | — | US | disclosed |
| US-4212872-A | ANTICOAGULANTS | BEECHAM GROUP LIMITED (GB) | 1980-07-15 | — | — | US | disclosed |
| US-4113728-A | ANTICOAGULANTS | BEECHAM GROUP LIMITED (GB) | 1978-09-12 | — | — | US | disclosed |