⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7200857 | 0.98 | — | — | |
| SCHEMBL9586346 | 0.91 | PRCP (0.31) | — | |
| SCHEMBL11279289 | 0.91 | PRCP (0.31) | — | |
| SCHEMBL1448263 | 0.77 | SOS1 (0.33) | — | |
| SCHEMBL6024634 | 0.70 | SOS1 (0.31) | — | |
| SCHEMBL9691016 | 0.69 | — | — | |
| SCHEMBL28282 | 0.62 | — | — | |
| SCHEMBL11352150 | 0.62 | PRCP (0.31) | — | |
| SCHEMBL11212318 | 0.60 | CCR5 (0.36) | — | |
| SCHEMBL30277277 | 0.60 | CCR5 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750688-A | REACTING AN HALOGENATED AMINE WITH AN OXYBENZOIC ESTER; THEN A 2-(OXYPHENYL-)BENZOTHIOPHENE COMPOUND | ELI LILLY AND COMPANY (US) | 1998-05-12 | — | — | US | claimed |
| EP-0729956-A1 | Benzothiophene compounds, intermediates, compositions, and methods | ELI LILLY AND COMPANY (US) | 1996-09-04 | — | — | EP | claimed |
| EP-0548226-A1 | MONOSACCHARIDES HAVING ANTI-PROLIFERATION AND ANTI-INFLAMMATORY ACTIVITY, COMPOSITIONS AND USES THEREOF | GREENWICH PHARMACEUTICALS INCORPORATED (US) | 1993-06-30 | — | — | EP | claimed |
| WO-1992004359-A2 | MONOSACCHARIDES HAVING ANTI-PROLIFERATION AND ANTI-INFLAMMATORY ACTIVITY, COMPOSITIONS AND USES THEREOF | GREENWICH PHARMACEUTICALS, INC. (US) | 1992-03-19 | — | — | WO | claimed |
| US-5298494-A | Glucofuranose derivatives | GREENWICH PHARMACEUTICALS INCORPORATED (US) | 1994-03-29 | — | — | US | disclosed |
| EP-0548226-A1 | MONOSACCHARIDES HAVING ANTI-PROLIFERATION AND ANTI-INFLAMMATORY ACTIVITY, COMPOSITIONS AND USES THEREOF | GREENWICH PHARMACEUTICALS INCORPORATED (US) | 1993-06-30 | — | — | EP | disclosed |
| WO-1992004359-A2 | MONOSACCHARIDES HAVING ANTI-PROLIFERATION AND ANTI-INFLAMMATORY ACTIVITY, COMPOSITIONS AND USES THEREOF | GREENWICH PHARMACEUTICALS, INC. (US) | 1992-03-19 | — | — | WO | disclosed |