Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A12 | P48065 | 4/20 | 0.41 |
| ▸ | SLC6A11 | P48066 | 4/20 | 0.41 |
| ▸ | SLC6A13 | Q9NSD5 | 4/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | ABAT | P80404 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2466288 | 0.79 | SLC6A12 (0.50) | SLC6A12SLC6A11SLC6A13GRM2GRM5 | |
| SCHEMBL16512741 | 0.79 | SLC6A12 (0.50) | SLC6A12SLC6A11SLC6A13GRM2GRM5 | |
| SCHEMBL16499292 | 0.79 | SLC6A12 (0.50) | SLC6A12SLC6A11SLC6A13GRM2GRM5 | |
| SCHEMBL9836735 | 0.76 | TSHR (0.33) | — | |
| SCHEMBL14535851 | 0.76 | TSHR (0.33) | — | |
| SCHEMBL25497628 | 0.75 | SLC6A12 (0.35) | SLC6A12SLC6A11SLC6A13 | |
| SCHEMBL11747344 | 0.74 | SLC6A12 (0.38) | SLC6A12SLC6A11SLC6A13GRM5HSD11B1 | |
| SCHEMBL11743735 | 0.74 | SLC6A12 (0.38) | SLC6A12SLC6A11SLC6A13GRM5HSD11B1 | |
| SCHEMBL2466422 | 0.74 | SLC6A12 (0.38) | SLC6A12SLC6A11SLC6A13GRM5HSD11B1 | |
| SCHEMBL9792876 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4340732-A | Butenolide herbicides and process for their preparation | INTERNATIONAL DEVELOPMENT RESEARCH CENTRE OTTAWA ONTARIO CANADA K1G 3H9 A COORP OF CANADA (CA) | 1982-07-20 | — | — | US | disclosed |