Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.34 |
| ▸ | FDPS | P14324 | 9/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26632587 | 0.93 | TSHR (0.42) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL10598543 | 0.93 | TSHR (0.42) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL9835291 | 0.83 | — | — | |
| SCHEMBL6257463 | 0.83 | FFAR1 (0.42) | — | |
| SCHEMBL2727626 | 0.78 | TSHR (0.42) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL11805476 | 0.78 | TSHR (0.42) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL19798086 | 0.77 | FDPS (0.41) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL20856568 | 0.77 | TSHR (0.53) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL20856500 | 0.77 | TSHR (0.53) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL21549958 | 0.77 | TSHR (0.53) | TSHRTHRBGGPS1FDPSSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4319030-A | Alkylated diaza-spirodecanes | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-03-09 | — | — | US | disclosed |