Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 1.00 |
| ▸ | NPC1 | O15118 | 9/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.77 |
| ▸ | MAPT | P10636 | 5/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | LMNA | P02545 | 4/20 | 0.77 |
| ▸ | HTT | P42858 | 3/20 | 0.77 |
| ▸ | USP2 | O75604 | 3/20 | 0.77 |
| ▸ | TP53 | P04637 | 2/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.75 |
| ▸ | XBP1 | P17861 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.73 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.73 |
| ▸ | TNF | P01375 | 2/20 | 0.73 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.73 |
| ▸ | PKM | P14618 | 1/20 | 0.73 |
| ▸ | MITF | O75030 | 2/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25720375 | 0.87 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1KDM4EMAPT | |
| SCHEMBL10676012 | 0.83 | RAB9A (0.71) | RAB9ASMN1; SMN2NPC1KDM4EMAPT | |
| SCHEMBL1777363 | 0.81 | RAB9A (0.68) | RAB9ASMN1; SMN2NPC1KDM4EMAPT | |
| SCHEMBL10668803 | 0.81 | HSD17B10 (0.76) | RAB9ASMN1; SMN2NPC1KDM4EMAPT | |
| SCHEMBL10679811 | 0.81 | NPC1 (0.78) | RAB9ASMN1; SMN2NPC1KDM4EMAPT | |
| Pyridine SCHEMBL10677617 | 0.79 | NPC1 (0.69) | RAB9ASMN1; SMN2NPC1KDM4EMAPT | |
| SCHEMBL24054803 | 0.78 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1KDM4EMAPT | |
| SCHEMBL10672530 | 0.78 | NPC1 (0.77) | RAB9ASMN1; SMN2NPC1KDM4EMAPT | |
| SCHEMBL30227674 | 0.78 | NPC1 (0.77) | RAB9ASMN1; SMN2NPC1KDM4EMAPT | |
| SCHEMBL10669253 | 0.77 | RAB9A (0.69) | RAB9ASMN1; SMN2NPC1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0059698-A1 | Heterocyclic carboxamides, compositions containing such compounds, processes for their preparation and methods of treatment therewith | AB LEO (SE) | 1982-09-08 | — | — | EP | disclosed |