Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | BLM | P54132 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | USP2 | O75604 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 3/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.63 |
| ▸ | RECQL | P46063 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.63 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.63 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.63 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.63 |
| ▸ | CSNK2A3 | Q8NEV1 | 3/20 | 0.63 |
| ▸ | NSD2 | O96028 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | MTOR | P42345 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1323094 | 0.98 | CYP19A1 (0.69) | CYP19A1MEN1KMT2ABLMSMN1; SMN2 | |
| SCHEMBL10524500 | 0.95 | CYP19A1 (0.73) | CYP19A1MEN1KMT2ABLMSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11150067 | 0.94 | CYP19A1 (0.71) | CYP19A1MEN1KMT2ABLMSMN1; SMN2 | |
| SCHEMBL14228462 | 0.92 | CYP19A1 (0.61) | CYP19A1MEN1KMT2ABLMSMN1; SMN2 | |
| SCHEMBL1323801 | 0.90 | CYP19A1 (0.59) | CYP19A1MEN1KMT2ABLMSMN1; SMN2 | |
| SCHEMBL10523397 | 0.89 | MEN1 (0.75) | CYP19A1MEN1KMT2ABLMSMN1; SMN2 | |
| SCHEMBL4885984 | 0.88 | CYP19A1 (0.68) | CYP19A1MEN1KMT2ABLMSMN1; SMN2 | |
| SCHEMBL11517791 | 0.88 | CYP19A1 (0.68) | CYP19A1MEN1KMT2ABLMSMN1; SMN2 | |
| SCHEMBL29350310 | 0.88 | CYP19A1 (0.68) | CYP19A1MEN1KMT2ABLMSMN1; SMN2 | |
| SCHEMBL10620370 | 0.87 | CYP19A1 (0.62) | CYP19A1MEN1KMT2ABLMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0021622-B1 | 1-(AMINOALKYLAMINO)-5,8-DIHYDROXY-4-SUBSTITUTED-ANTHRAQUINONES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMERICAN CYANAMID COMPANY (US) | 1982-10-20 | — | — | EP | claimed |
| US-4275009-A | ANTITUMOR, CHELATION | AMERICAN CYANAMID COMPANY (US) | 1981-06-23 | — | — | US | claimed |
| EP-0021622-A1 | 1-(Aminoalkylamino)-5,8-dihydroxy-4-substituted-anthraquinones, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1981-01-07 | — | — | EP | claimed |
| US-4275009-A | ANTITUMOR, CHELATION | AMERICAN CYANAMID COMPANY (US) | 1981-06-23 | — | — | US | disclosed |
| EP-0021622-A1 | 1-(Aminoalkylamino)-5,8-dihydroxy-4-substituted-anthraquinones, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1981-01-07 | — | — | EP | disclosed |