Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.53 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.53 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | THPO | P40225 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10620370 | 0.95 | CYP19A1 (0.62) | CYP19A1TP53MEN1KMT2ACYP3A4 | |
| SCHEMBL1323094 | 0.92 | CYP19A1 (0.69) | CYP19A1TP53MEN1KMT2ACYP3A4 | |
| SCHEMBL11279729 | 0.90 | CYP19A1 (0.71) | CYP19A1TP53MEN1KMT2ACYP3A4 | |
| SCHEMBL10624602 | 0.89 | CYP19A1 (0.57) | CYP19A1TP53MEN1KMT2ACYP3A4 | |
| SCHEMBL10524500 | 0.86 | CYP19A1 (0.73) | CYP19A1TP53MEN1KMT2ACYP3A4 | |
| SCHEMBL14228462 | 0.85 | CYP19A1 (0.61) | CYP19A1TP53MEN1KMT2ACYP3A4 | |
| Hydrochloric Acid SCHEMBL11150067 | 0.84 | CYP19A1 (0.71) | CYP19A1TP53MEN1KMT2ACYP3A4 | |
| SCHEMBL10619827 | 0.82 | MEN1 (0.57) | CYP19A1TP53MEN1KMT2ACYP3A4 | |
| SCHEMBL10622164 | 0.82 | CYP19A1 (0.57) | CYP19A1TP53MEN1KMT2ACYP3A4 | |
| SCHEMBL10523397 | 0.80 | MEN1 (0.75) | CYP19A1TP53MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8058460-B2 | Near infrared fluorophore for the selective labelling of membranes in cells | Universität Heidelberg (DE) | 2011-11-15 | — | — | US | disclosed |
| US-8058460-B2 | Near infrared fluorophore for the selective labelling of membranes in cells | Universität Heidelberg (DE) | 2011-11-15 | — | — | US | disclosed |
| US-8058460-B2 | Near infrared fluorophore for the selective labelling of membranes in cells | Universität Heidelberg (DE) | 2011-11-15 | — | — | US | disclosed |
| US-20090291467-A1 | Near Infrared Fluorophore for the Selective Labelling of Membranes in Cells | UNIVERSITAT HEIDELBERG (DE) | 2009-11-26 | — | — | US | disclosed |
| US-20090291467-A1 | Near Infrared Fluorophore for the Selective Labelling of Membranes in Cells | UNIVERSITAT HEIDELBERG (DE) | 2009-11-26 | — | — | US | disclosed |
| US-20090291467-A1 | Near Infrared Fluorophore for the Selective Labelling of Membranes in Cells | UNIVERSITAT HEIDELBERG (DE) | 2009-11-26 | — | — | US | disclosed |
| EP-2046894-A2 | NEAR INFRARED FLUOROPHORE FOR THE SELECTIVE LABELLING OF MEMBRANES IN CELLS | Universität Heidelberg (DE) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008037394-A2 | NEAR INFRARED FLUOROPHORE FOR THE SELECTIVE LABELLING OF MEMBRANES IN CELLS | Universität Heidelberg (DE) | 2008-04-03 | — | — | WO | disclosed |
| EP-1905801-A1 | Near infrared fluorophore for the selective labelling of membranes in cells | Universität Heidelberg (DE) | 2008-04-02 | — | — | EP | disclosed |
| EP-1905801-A1 | Near infrared fluorophore for the selective labelling of membranes in cells | Universität Heidelberg (DE) | 2008-04-02 | — | — | EP | disclosed |