Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11280626 | 0.87 | GAA (0.43) | GAALMNAPARP10ALDH1A1NQO1 | |
| SCHEMBL9585939 | 0.85 | GAA (0.43) | GAALMNAPARP10ALDH1A1SMN1; SMN2 | |
| SCHEMBL11061511 | 0.85 | KMT2A (0.46) | LMNAPARP10ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL2357779 | 0.85 | KMT2A (0.46) | LMNAPARP10ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL10585508 | 0.85 | NQO1 (0.44) | LMNAPARP10ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL2357783 | 0.85 | KMT2A (0.46) | LMNAPARP10ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11230305 | 0.85 | CA12 (0.36) | GAALMNAMAPTMAPK1PARP10 | |
| SCHEMBL10543110 | 0.82 | GAA (0.40) | GAALMNAMAPTMAPK1ABCB11 | |
| SCHEMBL11043611 | 0.82 | GAA (0.40) | GAALMNAMAPTMAPK1ABCB11 | |
| SCHEMBL10982856 | 0.80 | FFAR1 (0.47) | SMN1; SMN2ADAM17PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309350-A | CONDENSATION OF PHENYLACETIC ESTER WITH DIALKYL OXALATE IN PRESENCE OF BASIC CATALYST, ACIDIFICATION, HYDROXYMETHYLATION, DEHYDRATION | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1982-01-05 | — | — | US | disclosed |
| US-4262014-A | Insecticidal esters | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1981-04-14 | — | — | US | disclosed |
| US-4220591-A | Insecticidal esters | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1980-09-02 | — | — | US | disclosed |