SCHEMBL2357779

SCHEMBL2357779

CCOc1ccc(C2(C(=O)O)CC2(Cl)Cl)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.46
TET3 O43151 1/20 0.46
FBXL19 Q6PCT2 1/20 0.46
CXXC5 Q7LFL8 1/20 0.46
TET1 Q8NFU7 1/20 0.46
KDM2B Q8NHM5 1/20 0.46
CXXC4 Q9H2H0 1/20 0.46
KDM2A Q9Y2K7 1/20 0.46
MEN1 O00255 2/20 0.44
TSHR P16473 1/20 0.44
NQO1 P15559 1/20 0.44
PARP10 Q53GL7 1/20 0.44
PLA2G4B P0C869 1/20 0.43
POLB P06746 3/20 0.42
HTT P42858 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
TDP1 Q9NUW8 2/20 0.41
NPC1 O15118 1/20 0.41
PLK1 P53350 1/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11061511 1.00 KMT2A (0.46) KMT2ATET3FBXL19CXXC5TET1
SCHEMBL2357783 1.00 KMT2A (0.46) KMT2ATET3FBXL19CXXC5TET1
SCHEMBL10585508 0.88 NQO1 (0.44) KMT2ATET3FBXL19CXXC5TET1
SCHEMBL11280832 0.86 KMT2A (0.47) KMT2ATET3FBXL19CXXC5TET1
SCHEMBL31687589 0.85 MEN1 (0.57) KMT2AMEN1TSHRPLA2G4BTP53
SCHEMBL11279733 0.85 GAA (0.43) KMT2AMEN1NQO1PARP10POLB
SCHEMBL31687659 0.85 KMT2A (0.40) KMT2ATET3FBXL19CXXC5TET1
SCHEMBL11275114 0.84 KMT2A (0.46) KMT2ATET3FBXL19CXXC5TET1
SCHEMBL10933849 0.84 KMT2A (0.46) KMT2ATET3FBXL19CXXC5TET1
SCHEMBL31687657 0.84 MEN1 (0.56) KMT2AMEN1TSHRPLA2G4BTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 258 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2325385-B1 COMPOSITION FOR THE IMPREGNATION OF FIBERS, FABRICS AND NETTINGS IMPARTING A PROTECTIVE ACTIVITY AGAINST PESTS BASF SE (DE) 2017-10-04 EP claimed
EP-1697578-B1 COMPOSITION FOR THE IMPREGNATION OF FIBERS, FABRICS AND NETTINGS IMPARTING A PROTECTIVE ACTIVITY AGAINST PESTS BASF SE (DE) 2011-08-31 EP claimed
US-7793920-B2 barrier against insect; the net structure made of polymer fibers is impregnated with an insecticide; preventing the low flying insects from entering open-air area; black color; invisible to certain insects VESTERGAARD SA (CH) 2010-09-14 US claimed
EP-1566996-B1 METHOD OF PROTECTING SEEDS TREATED WITH A PHYTOTOXIC AGENT MONSANTO TECHNOLOGY LLC (US) 2009-11-11 EP claimed
US-20070196412-A1 Composition for the impregnation of fibers, fabrics and nettings imparting a protective activity against pests BASF AKTIENGESELLSCHAFT (DE) 2007-08-23 US claimed
EP-1697578-A2 COMPOSITION FOR THE IMPREGNATION OF FIBERS, FABRICS AND NETTINGS IMPARTING A PROTECTIVE ACTIVITY AGAINST PESTS BASF AKTIENGESELLSCHAFT (DE) 2006-09-06 EP claimed
WO-2005064072-A2 COMPOSITION FOR THE IMPREGNATION OF FIBERS, FABRICS AND NETTINGS IMPARTING A PROTECTIVE ACTIVITY AGAINST PESTS BASF AKTIENGESELLSCHAFT (DE) 2005-07-14 WO claimed
US-20050132500-A1 Composition for impregnation of fibers, fabrics and nettings imparting a protective activity against pests BASF AKTIENGESELLSCHAFT (DE) 2005-06-23 US claimed
EP-1411764-B1 A FENCING DISEASE CONTROL TEXTILES APS (DK) 2004-12-29 EP claimed
EP-1411764-A1 A FENCING Disease Control Textiles APS (DK) 2004-04-28 EP claimed
US-20040004210-A1 Fencing VESTERGAARD SA (CH) 2004-01-08 US claimed
WO-2003003827-A1 A FENCING DISEASE CONTROL TEXTILES APS (DK) 2003-01-16 WO claimed
WO-2001037662-A1 COMPOSITION FOR IMPREGNATION OF FABRICS AND NETTINGS DCT APS (DK) 2001-05-31 WO claimed
US-5147645-A Insecticides, miticides, nematocides BASF AKTIENGESELLSCHAFT (DE) 1992-09-15 US claimed
US-4855446-A Process for the resolution of racemates using lactone esters THE SHERWIN WILLIAMS COMPANY (US) 1989-08-08 US claimed
US-4501908-A 2,3-Isopropylidene ribonic acid, 1,4-lactones HOFFMANN-LA ROCHE INC. (US) 1985-02-26 US claimed
EP-0060445-A1 Process for the resolution of racemates and lactone esters used in said process F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1982-09-22 EP claimed
US-4220591-A Insecticidal esters COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) 1980-09-02 US claimed
JP-59155350-A None JP disclosed
US-4220591-A Insecticidal esters COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) 1980-09-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070196412-A1 Composition for the impregnation of fibers, fabrics and nettings imparting a protective activity against pests GAP43, GRN, DDT KMT2A 1837/4885TET3 2338/4885FBXL19 2067/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.