Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | ECE2 | P0DPD6 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11277514 | 0.86 | HTT (0.60) | HTTECE2HPGDKDM4EGAA | |
| SCHEMBL11286791 | 0.85 | HTT (0.59) | HTTECE2HPGDKDM4EALDH1A1 | |
| SCHEMBL11278425 | 0.85 | HTT (0.59) | HTTECE2HPGDKDM4EALDH1A1 | |
| SCHEMBL17559350 | 0.81 | HTT (0.56) | HTTECE2HPGDKDM4EGAA | |
| SCHEMBL11276769 | 0.80 | SMN1; SMN2 (0.66) | HTTECE2HPGDKDM4EGAA | |
| SCHEMBL11286529 | 0.79 | PTGS1 (0.59) | HTTHPGDKDM4EGAAL3MBTL1 | |
| SCHEMBL17559386 | 0.79 | HTT (0.54) | HTTECE2HPGDKDM4EGAA | |
| SCHEMBL19059444 | 0.77 | SMN1; SMN2 (0.62) | HPGDKDM4EGAAL3MBTL1ALDH1A1 | |
| SCHEMBL11281767 | 0.77 | ALDH1A1 (0.44) | HTTKDM4EALDH1A1 | |
| SCHEMBL11265562 | 0.77 | ALDH1A1 (0.44) | HTTKDM4EALDH1A1HSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327022-A | Heterocyclic alkyl naphthols | STERLING DRUG INC. (US) | 1982-04-27 | — | — | US | disclosed |
| US-4169108-A | 5(OR 6)-[(Substituted-amino)alkyl]-2,3-naphthalenediols | STERLING DRUG INC. (US) | 1979-09-25 | — | — | US | disclosed |