Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MITF | O75030 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | RAD52 | P43351 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27763982 | 0.79 | GAA (0.41) | MAPTALDH1A1CYP1A2GAAKMT2A | |
| SCHEMBL4857909 | 0.69 | SMN1; SMN2 (0.55) | MAPTALDH1A1HSP90AA1CYP1A2CYP2D6 | |
| SCHEMBL11273549 | 0.67 | GAA (1.00) | MAPTALDH1A1CYP1A2CYP2C19GAA | |
| SCHEMBL14520700 | 0.67 | KDM4E (0.58) | MAPTALDH1A1HSP90AA1CYP1A2CYP2D6 | |
| SCHEMBL2481449 | 0.65 | ALDH1A1 (0.41) | MAPTALDH1A1HSP90AA1CYP1A2CYP2D6 | |
| SCHEMBL31350638 | 0.64 | KDM4E (0.45) | MAPTALDH1A1HSP90AA1CYP1A2CYP2D6 | |
| SCHEMBL31350484 | 0.64 | KDM4E (0.45) | MAPTALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL31350740 | 0.64 | KDM4E (0.49) | MAPTALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL24348510 | 0.64 | SMN1; SMN2 (0.58) | MAPTALDH1A1HSP90AA1CYP1A2CYP2D6 | |
| SCHEMBL2305957 | 0.63 | ALDH1A1 (0.38) | MAPTALDH1A1HSP90AA1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4366231-A | Photographic material containing a stabilizer, a process for its production, a development process, new pyrazoles, a process for their production and intermediate products | AGFA GEVAERT AKTIENGESELLSCHAFT (DE) | 1982-12-28 | — | — | US | disclosed |