SCHEMBL11280339

SCHEMBL11280339

O=C(O)c1ccc(C(=O)Oc2cccc(C(=O)O)c2)cc1

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.59
KMT2A Q03164 7/20 0.56
MEN1 O00255 1/20 0.56
MAPT P10636 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
ALDH1A1 P00352 1/20 0.54
ESR1 P03372 2/20 0.53
ESR2 Q92731 2/20 0.53
PARP10 Q53GL7 1/20 0.51
NR4A2 P43354 1/20 0.51
KMO O15229 1/20 0.50
PRSS1 P07477 1/20 0.50
ACR P10323 1/20 0.50
SRD5A2 P31213 1/20 0.49
SERPINE1 P05121 1/20 0.49
RXRA P19793 1/20 0.49
RXRB P28702 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11270798 0.98 AKR1C3 (0.61) AKR1C3KMT2AMEN1MAPTTDP1
SCHEMBL8897103 0.94 AKR1C3 (0.67) AKR1C3KMT2AMEN1MAPTTDP1
SCHEMBL904445 0.93 KMT2A (0.53) AKR1C3KMT2AMEN1MAPTTDP1
SCHEMBL9356640 0.93 AKR1C3 (0.65) AKR1C3KMT2AMEN1MAPTTDP1
SCHEMBL546153 0.92 KMT2A (0.55) AKR1C3KMT2AMEN1MAPTTDP1
SCHEMBL8405844 0.91 ESR1 (0.56) AKR1C3KMT2AMEN1MAPTTDP1
SCHEMBL11196204 0.91 AKR1C3 (0.61) AKR1C3KMT2AMEN1MAPTTDP1
Ammonia Solution, Strong SCHEMBL8011408 0.91 KMT2A (0.53) AKR1C3KMT2AMEN1MAPTTDP1
SCHEMBL11319807 0.90 KMT2A (0.56) AKR1C3KMT2AMEN1MAPTTDP1
Isophthalic Acid SCHEMBL2889737 0.89 PARP10 (0.61) AKR1C3KMT2AMEN1MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0052927-A2 Stretched film structure of the poly-1,3-phenylene terephthalate type MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1982-06-02 EP disclosed