Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69046 | 0.85 | KMT2A (0.69) | KMT2AUSP2ARGAAMAPT | |
| SCHEMBL11281133 | 0.84 | KMT2A (0.56) | KMT2AUSP2ARGAAMAPT | |
| SCHEMBL11788500 | 0.79 | KMT2A (0.62) | KMT2AUSP2ARGAAMAPT | |
| SCHEMBL11276657 | 0.74 | MAPT (0.56) | KMT2AUSP2ARGAAMAPT | |
| SCHEMBL13754328 | 0.73 | KDM4E (0.59) | KMT2AUSP2GAAALDH1A1KDM4E | |
| SCHEMBL11363402 | 0.73 | KMT2A (1.00) | KMT2AUSP2GAAMAPTALDH1A1 | |
| SCHEMBL26967883 | 0.72 | KMT2A (0.54) | KMT2AUSP2ARGAAMAPT | |
| SCHEMBL3364773 | 0.71 | KMT2A (0.67) | KMT2AUSP2ARGAAMAPT | |
| SCHEMBL21408329 | 0.71 | KMT2A (0.67) | KMT2AUSP2ARGAAMAPT | |
| SCHEMBL2760357 | 0.71 | KMT2A (0.57) | KMT2AUSP2ARGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4345087-A | Process for preparing heteroarylbenzoxepin-acetic acids, precursors and derivatives thereof | AMERICAN HOECHST CORPORATION (US) | 1982-08-17 | — | — | US | disclosed |
| US-4124713-A | Oxopyridobenzoxepin-acetic acids and derivatives thereof useful as antiinflammatory and analgesic agents | AMERICAN HOECHST CORPORATION (US) | 1978-11-07 | — | — | US | disclosed |
| US-4117152-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | AMERICAN HOECHST CORPORATION (US) | 1978-09-26 | — | — | US | disclosed |
| US-4107321-A | ANTIINFLAMMATORY AGENTS, ANALGESICS | AMERICAN HOECHST CORPORATION (US) | 1978-08-15 | — | — | US | disclosed |
| US-4107177-A | CYCLIZING (CARBOXYTHIENYLOXY)BENZENEACETIC ACID WITH DEHYDRATING AGENT | AMERICAN HOECHST CORPORATION (US) | 1978-08-15 | — | — | US | disclosed |
| US-4101559-A | ANTIINFLAMMATORY, ANALGESIC | AMERICAN HOECHST CORPORATION (US) | 1978-07-18 | — | — | US | disclosed |
| US-4081457-A | ANTIINFLAMMATORY, ANALGESIC | AMERICAN HOECHST CORPORATION (US) | 1978-03-28 | — | — | US | disclosed |
| US-4025640-A | ANTIINFLAMMATORY, ANALGESIC | AMERICAN HOECHST CORPORATION (US) | 1977-05-24 | — | — | US | disclosed |