SCHEMBL69046

SCHEMBL69046

CCOC(=O)c1c(C(=O)OCC)c(C)n(C)c1C

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.69
USP2 O75604 1/20 0.65
KDM4E B2RXH2 1/20 0.53
MAPT P10636 3/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
AR P10275 1/20 0.53
GAA P10253 2/20 0.51
PKM P14618 1/20 0.51
ALDH1A1 P00352 3/20 0.50
HPGD P15428 3/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
TSHR P16473 2/20 0.49
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11788500 0.90 KMT2A (0.62) KMT2AUSP2KDM4EMAPTSMN1; SMN2
SCHEMBL11280355 0.85 KMT2A (0.57) KMT2AUSP2KDM4EMAPTSMN1; SMN2
SCHEMBL11281133 0.83 KMT2A (0.56) KMT2AUSP2MAPTSMN1; SMN2AR
SCHEMBL11276657 0.83 MAPT (0.56) KMT2AUSP2KDM4EMAPTSMN1; SMN2
SCHEMBL11363402 0.82 KMT2A (1.00) KMT2AUSP2KDM4EMAPTSMN1; SMN2
SCHEMBL26967883 0.82 KMT2A (0.54) KMT2AUSP2KDM4EMAPTSMN1; SMN2
SCHEMBL3364773 0.81 KMT2A (0.67) KMT2AUSP2MAPTSMN1; SMN2AR
SCHEMBL21408329 0.81 KMT2A (0.67) KMT2AUSP2MAPTSMN1; SMN2AR
SCHEMBL2760357 0.81 KMT2A (0.57) KMT2AUSP2KDM4EMAPTSMN1; SMN2
SCHEMBL23127813 0.80 KMT2A (0.53) KMT2AUSP2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 KMT2A 1042/4885USP2 2928/4885KDM4E 717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.