Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | EDNRB | P24530 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EED | O75530 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11282581 | 0.88 | EDNRB (0.42) | EDNRBEDNRANPC1KDM4E | |
| SCHEMBL11291121 | 0.87 | EDNRB (0.39) | EDNRBEDNRAKMT2ANPC1KDM4E | |
| SCHEMBL11291123 | 0.86 | EDNRB (0.41) | EDNRBEDNRANPC1KDM4E | |
| SCHEMBL11281334 | 0.84 | EDNRB (0.37) | EDNRBEDNRANPC1KDM4E | |
| SCHEMBL10508077 | 0.80 | GAA (0.52) | SMN1; SMN2LMNACYP1A2CYP2C19HTT | |
| SCHEMBL10847421 | 0.79 | EDNRB (0.37) | EDNRBEDNRANPC1KDM4E | |
| SCHEMBL11042703 | 0.78 | KDM4E (0.41) | EDNRBEDNRANPC1KDM4E | |
| SCHEMBL11155912 | 0.78 | NPC1 (0.41) | KMT2ANPC1KDM4E | |
| SCHEMBL11155674 | 0.76 | CA2 (0.39) | CYP1A2NPC1KDM4E | |
| SCHEMBL11041308 | 0.74 | EDNRB (0.38) | SMN1; SMN2CYP1A2CYP2C19EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339267-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-07-13 | — | — | US | claimed |
| US-4339267-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-07-13 | — | — | US | disclosed |