SCHEMBL11280508

SCHEMBL11280508

CCCCC(CC)C(O)C#CI

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
LMNA P02545 1/20 0.33
CA2 P00918 3/20 0.32
MAPK1 P28482 1/20 0.32
CA1 P00915 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL735318 0.87 ALDH1A1 (0.39) ALDH1A1LMNACA2MAPK1CA1
SCHEMBL28505051 0.79 ALDH1A1 (0.37) ALDH1A1LMNACA2MAPK1CA1
SCHEMBL3020218 0.76 ALDH1A1 (0.41) ALDH1A1LMNACA2MAPK1CA1
SCHEMBL14456810 0.75 TSHR (0.37) ALDH1A1LMNACA2MAPK1CA1
SCHEMBL179938 0.75 ALDH1A1 (0.37) ALDH1A1LMNACA2MAPK1CA1
SCHEMBL423728 0.71 ALDH1A1 (0.44) ALDH1A1LMNACA2MAPK1CA1
SCHEMBL14125822 0.71 ALDH1A1 (0.44) ALDH1A1LMNACA2MAPK1CA1
SCHEMBL12209116 0.71 ALDH1A1 (0.44) ALDH1A1LMNACA2MAPK1CA1
SCHEMBL11832228 0.71 ALDH1A1 (0.44) ALDH1A1LMNACA2MAPK1CA1
SCHEMBL11702097 0.70 HMGCR (0.41) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0046582-A1 Inorganic catalyst for alkoxylation of alcohols Conoco Inc. (formerly called : DU PONT HOLDINGS , INC.) (US) 1982-03-03 EP disclosed