Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 20/20 | 0.77 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11123161 | 0.87 | ACE (1.00) | ACEACE2 | |
| SCHEMBL1792093 | 0.87 | ACE (1.00) | ACEACE2 | |
| SCHEMBL1792089 | 0.87 | ACE (1.00) | ACEACE2 | |
| SCHEMBL11272136 | 0.85 | ACE (0.87) | ACEACE2 | |
| SCHEMBL10976266 | 0.84 | ACE (0.78) | ACEACE2 | |
| SCHEMBL11283912 | 0.84 | ACE (0.78) | ACEACE2 | |
| SCHEMBL11123651 | 0.84 | ACE (1.00) | ACEACE2 | |
| SCHEMBL11123648 | 0.84 | ACE (1.00) | ACEACE2 | |
| SCHEMBL11123656 | 0.84 | ACE (1.00) | ACEACE2 | |
| SCHEMBL10975992 | 0.84 | ACE (1.00) | ACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0053017-A1 | Amide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-06-02 | — | — | EP | disclosed |