Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 18/20 | 0.78 |
| ▸ | ACE2 | Q9BYF1 | 11/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11283912 | 1.00 | ACE (0.78) | ACEACE2 | |
| SCHEMBL11291682 | 0.92 | ACE (0.67) | ACEACE2 | |
| SCHEMBL11291684 | 0.92 | ACE (0.67) | ACEACE2 | |
| SCHEMBL11122708 | 0.88 | ACE (1.00) | ACEACE2 | |
| SCHEMBL11122713 | 0.88 | ACE (1.00) | ACEACE2 | |
| SCHEMBL11120609 | 0.86 | ACE (0.82) | ACEACE2 | |
| SCHEMBL11120692 | 0.86 | ACE (0.82) | ACEACE2 | |
| SCHEMBL11286191 | 0.85 | ACE (0.80) | ACEACE2 | |
| SCHEMBL11286198 | 0.85 | ACE (0.80) | ACEACE2 | |
| SCHEMBL11280664 | 0.84 | ACE (0.77) | ACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0053017-B1 | AMIDE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-02-20 | — | — | EP | claimed |
| EP-0053017-A1 | Amide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-06-02 | — | — | EP | claimed |
| EP-0053017-A1 | Amide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-06-02 | — | — | EP | disclosed |