Chloromethane

Chloromethane

SCHEMBL1128070

C=C(C)C(=O)OC(C)N(CC)CC.CCl

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
ALDH1A1 P00352 2/20 0.35
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14873 0.96 TSHR (0.44) TSHRALDH1A1THRB
SCHEMBL28273631 0.96 TSHR (0.44) TSHRALDH1A1THRB
Ammonia Solution, Strong SCHEMBL28263372 0.94 TSHR (0.42) TSHRALDH1A1THRB
Hydrochloric Acid SCHEMBL9258461 0.94 TSHR (0.42) TSHRALDH1A1THRB
Acetic Acid SCHEMBL27216306 0.93 TSHR (0.41) TSHRALDH1A1THRB
Isopropyl Alcohol SCHEMBL20480785 0.93 TSHR (0.41) TSHRALDH1A1THRB
Boric Acid SCHEMBL8763863 0.91 TSHR (0.40) TSHRALDH1A1THRB
Methacrylic Acid SCHEMBL1060299 0.91 TSHR (0.40) TSHRALDH1A1THRB
SCHEMBL8106923 0.91 TSHR (0.40) TSHRALDH1A1THRB
Phosphoric Acid SCHEMBL28578414 0.89 TSHR (0.39) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2109441-B1 POLYSILOXANE BLOCK COPOLYMERS BASF SE (DE) 2016-01-27 EP claimed
US-8378038-B2 Polysiloxane block copolymers BASF SE (DE) 2013-02-19 US claimed
US-8148318-B2 Home or fabric care compositions comprising certain dye-polymer complexes BASF SE (DE) 2012-04-03 US claimed
US-8147814-B2 Personal care compositions comprising certain dye-polymer complexes BASF SE (DE) 2012-04-03 US claimed
US-20100303750-A1 POLYSILOXANE BLOCK COPOLYMERS KOROSKENYI BALINT 2010-12-02 US claimed
US-7732525-B2 Polymers for paper and paperboard coatings CIBA SPECIALTY CHEMICALS WATER TREATMENTS LIMITED (GB) 2010-06-08 US claimed
EP-2109441-A2 POLYSILOXANE BLOCK COPOLYMERS Ciba Holding Inc. (CH) 2009-10-21 EP claimed
EP-2046932-A2 COMPOSITION FOR IMPROVING WETTABILITY OF SURFACES Ciba Holding Inc. (CH) 2009-04-15 EP claimed
US-20080199418-A1 Polysiloxane block copolymers BASF SE (DE) 2008-08-21 US claimed
WO-2008095822-A2 POLYSILOXANE BLOCK COPOLYMERS CIBA HOLDING INC. (CH) 2008-08-14 WO claimed
US-20080033106-A1 Composition for improving wettability of surfaces CIBA SPECIALTY CHEMICALS CORP. 2008-02-07 US claimed
WO-2008015138-A2 COMPOSITION FOR IMPROVING WETTABILITY OF SURFACES CIBA HOLDING INC. (CH) 2008-02-07 WO claimed
EP-3116919-B1 NEW POLYELECTROLYTIC POLYMERS, PROCESS FOR THEIR PREPARATION AND USES THEREOF ITALMATCH CHEMICALS SPA (IT) 2020-08-26 EP disclosed
CN-106536574-B Polyelectrolyte polymers, Its Preparation Method And Use 伊塔尔麦奇化学股份公司 2019-02-22 CN disclosed
US-9771437-B2 Polyelectrolytic polymers, process for their preparation and uses thereof ITALMATCH CHEMICALS S.P.A. (IT) 2017-09-26 US disclosed
US-9669243-B2 Delivery of hydrophobic benefit agents from bodywashes and the like onto a keratinous substrate BASF SE (DE) 2017-06-06 US disclosed
EP-0892819-A1 OIL, WATER AND SOLVENT RESISTANT PAPER BY TREATMENT WITH FLUOROCHEMICAL COPOLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-01-27 EP disclosed
WO-1997039036-A1 OIL, WATER AND SOLVENT RESISTANT PAPER BY TREATMENT WITH FLUOROCHEMICAL COPOLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-10-23 WO disclosed
US-5674961-A SURFACE TREATMENT WITH PROTECTIVE COATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-10-07 US disclosed
US-4354907-A TERTIARY OR QUATERNARY SALTS OF AMINOALKYL ACRYLATES JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) 1982-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100303750-A1 POLYSILOXANE BLOCK COPOLYMERS KRT18, PUF60, SCNN1B TSHR 4325/4885ALDH1A1 2457/4885THRB 1165/4885
US-20080199418-A1 Polysiloxane block copolymers KRT18, PUF60, SCNN1B TSHR 4325/4885ALDH1A1 2457/4885THRB 1165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.