Methacrylic Acid

Methacrylic Acid

SCHEMBL1060299

C=C(C)C(=O)O.C=C(C)C(=O)OC(C)N(CC)CC

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.40
ALDH1A1 P00352 1/20 0.34
THRB P10828 1/20 0.34
PGR P06401 1/20 0.32
ADRA2A P08913 1/20 0.32
ADRA2B P18089 1/20 0.32
HTR2A P28223 1/20 0.32
HRH1 P35367 1/20 0.32
KCNH2 Q12809 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL27216306 0.95 TSHR (0.41) TSHRALDH1A1THRBPGRADRA2A
SCHEMBL14873 0.94 TSHR (0.44) TSHRALDH1A1THRBPGRADRA2A
SCHEMBL28273631 0.94 TSHR (0.44) TSHRALDH1A1THRBPGRADRA2A
Ammonia Solution, Strong SCHEMBL28263372 0.93 TSHR (0.42) TSHRALDH1A1THRBPGRADRA2A
Hydrochloric Acid SCHEMBL9258461 0.93 TSHR (0.42) TSHRALDH1A1THRBPGRADRA2A
Isopropyl Alcohol SCHEMBL20480785 0.91 TSHR (0.41) TSHRALDH1A1THRB
Chloromethane SCHEMBL1128070 0.91 TSHR (0.41) TSHRALDH1A1THRB
Boric Acid SCHEMBL8763863 0.89 TSHR (0.40) TSHRALDH1A1THRB
SCHEMBL8106923 0.89 TSHR (0.40) TSHRALDH1A1THRB
Acrylic Acid SCHEMBL7775516 0.88 TSHR (0.37) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4652443-A Slow-release composite and process for producing the same JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) 1987-03-24 US claimed
EP-0130409-A2 Slow-release composite and process for producing the same Takeda Chemical Industries, Ltd. (JP) 1985-01-09 EP claimed
CN-108290990-A Binding property polymer and medical adhesive adhesive preparation 帝国制药株式会社 2018-07-17 CN disclosed
US-20150353596-A1 17-Substituted Steroid Compounds HOLLIS-EDEN PHARMACEUTICALS, INC. 2015-12-10 US disclosed
US-9115168-B2 Steroids having 7-oxygen and 17-heteroaryl substitution-3 NEURMEDIX, INC. (US) 2015-08-25 US disclosed
US-9102702-B2 Steroids having 7-oxygen and 17-heteroaryl substitution-2 NEURMEDIX INC. (US) 2015-08-11 US disclosed
US-20140018337-A1 Steroids Having 7-Oxygen and 17-Heteroaryl Substitution-3 Harbor Therapeutics, Inc. (US) 2014-01-16 US disclosed
US-20140018336-A1 Steroids Having 7-Oxygen and 17-Heteroaryl Substitution-2 Harbor Therapeutics, Inc. (US) 2014-01-16 US disclosed
US-8569275-B2 Steroids having 7-oxgen and 17-heteroaryl substitution Harbor Therapeutics, Inc. (US) 2013-10-29 US disclosed
CN-101688145-B Functional fluid CHIYODA CHEMICAL CO LTD 2013-03-27 CN disclosed
US-20120101052-A9 15-THIA STEROID COMPOUNDS AND COMPOSITIONS BIOVIE INC. 2012-04-26 US disclosed
US-20040138187-A1 Therapeutic treatment methods BIOVIE INC. 2004-07-15 US disclosed
WO-2004019953-A1 THERAPEUTIC TREATMENT METHODS HOLLIS-EDEN PHARMACEUTICALS, INC. (US) 2004-03-11 WO disclosed
EP-1372664-A1 USE OF CERTAIN STEROIDS FOR TREATMENT OF BLOOD CELL DEFICIENCIES Hollis-Eden Pharmaceuticals Inc. (US) 2004-01-02 EP disclosed
US-20030083231-A1 Blood cell deficiency treatment method BIOVIE INC. 2003-05-01 US disclosed
US-20030060425-A1 Immune modulation method using steroid compounds BIOVIE INC. 2003-03-27 US disclosed
WO-2002069977-A1 USE OF CERTAIN STEROIDS FOR TREATMENT OF BLOOD CELL DEFICIENCIES HOLLIS-EDEN PHARMACEUTICALS, INC. (US) 2002-09-12 WO disclosed
US-4800085-A Slow-release composite and process for producing the same JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) 1989-01-24 US disclosed
US-4652443-A Slow-release composite and process for producing the same JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) 1987-03-24 US disclosed
EP-0130409-A2 Slow-release composite and process for producing the same Takeda Chemical Industries, Ltd. (JP) 1985-01-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030060425-A1 Immune modulation method using steroid compounds HSD3B1, NR5A1, HSD17B1 TSHR 2359/4885ALDH1A1 2419/4885THRB 1652/4885
US-20030083231-A1 Blood cell deficiency treatment method THPO, HPGDS, MPL TSHR 1774/4885ALDH1A1 1150/4885THRB 1608/4885
US-20150353596-A1 17-Substituted Steroid Compounds HSD3B1, HSD3B2, HSD17B13 TSHR 3015/4885ALDH1A1 322/4885THRB 1300/4885
US-20140018336-A1 Steroids Having 7-Oxygen and 17-Heteroaryl Substitution-2 HSD3B1, HSD3B2, HSD17B13 TSHR 2793/4885ALDH1A1 413/4885THRB 1023/4885
US-20140018337-A1 Steroids Having 7-Oxygen and 17-Heteroaryl Substitution-3 HSD3B1, HSD3B2, HSD17B13 TSHR 2764/4885ALDH1A1 414/4885THRB 1066/4885
US-20120101052-A9 15-THIA STEROID COMPOUNDS AND COMPOSITIONS MPL, THPO, ALOX15 TSHR 937/4885ALDH1A1 1204/4885THRB 387/4885
US-20040138187-A1 Therapeutic treatment methods ELANE, ALOX15, IL15 TSHR 2231/4885ALDH1A1 800/4885THRB 1669/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.