Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.32 |
| ▸ | F2 | P00734 | 2/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.32 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.31 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.31 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599851 | 0.83 | TDP1 (0.48) | TDP1TP53KMT2AMEN1EPHX1 | |
| SCHEMBL8599848 | 0.83 | TDP1 (0.48) | TDP1TP53KMT2AMEN1EPHX1 | |
| Hydrochloric Acid SCHEMBL30596145 | 0.82 | TDP1 (0.47) | TDP1TP53KMT2AMEN1EPHX1 | |
| SCHEMBL11280746 | 0.81 | TDP1 (0.46) | TDP1KMT2AMEN1EPHX1ALDH1A1 | |
| SCHEMBL8597654 | 0.79 | MEN1 (0.50) | TDP1KMT2AMEN1PRSS1PRSS2 | |
| SCHEMBL8597658 | 0.79 | MEN1 (0.50) | TDP1KMT2AMEN1PRSS1PRSS2 | |
| SCHEMBL8596475 | 0.78 | TDP1 (0.43) | TDP1KMT2AMEN1EPHX1PRSS1 | |
| SCHEMBL8596471 | 0.78 | TDP1 (0.43) | TDP1KMT2AMEN1EPHX1PRSS1 | |
| Hydrochloric Acid SCHEMBL8597897 | 0.78 | MEN1 (0.49) | TDP1KMT2AMEN1PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL8596879 | 0.78 | MEN1 (0.49) | TDP1KMT2AMEN1PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348410-A | Cyclohexane carboxylic acid derivatives | NIPPON CHEMIPHAR CO., LTD. (JP) | 1982-09-07 | — | — | US | disclosed |