⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL2470336 | 0.91 | TSHR (0.50) | — | |
| Butane SCHEMBL9292387 | 0.91 | TSHR (0.50) | — | |
| Butane SCHEMBL3593 | 0.91 | — | — | |
| Butane SCHEMBL1734106 | 0.91 | — | — | |
| Butane SCHEMBL8628663 | 0.91 | TSHR (0.50) | — | |
| Butane SCHEMBL250788 | 0.83 | — | — | |
| Butane SCHEMBL814744 | 0.83 | — | — | |
| Butane SCHEMBL3181484 | 0.83 | — | — | |
| Butane SCHEMBL5851369 | 0.83 | — | — | |
| Butane SCHEMBL4586358 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4323362-A1 | METHODS OF PREPARING CARBANUCLEOSIDES USING AMIDES | GILEAD SCIENCES, INC. (US) | 2024-02-21 | — | — | EP | claimed |
| CN-112679512-A | Tributine intermediate and preparation method thereof | 南通诺泰生物医药技术有限公司 | 2021-04-20 | — | — | CN | claimed |
| EP-3081560-B1 | TAXANES COMPOUNDS, PREPARATION METHOD THEREFOR, AND USES THEREOF | JIANGSU TASLY DIYI PHARMACEUTICAL CO LTD (CN) | 2021-03-24 | — | — | EP | claimed |
| US-10253007-B2 | Taxanes compounds, preparation method therefor, and uses thereof | JIANGSU TASLY DIYI PHARMACEUTICAL CO., LTD. (CN) | 2019-04-09 | — | — | US | claimed |
| WO-2019067139-A1 | SELECTIVE REDUCTION OF CHLORODISILANES WITH TRI-N-BUTYL TIN HYDRIDE | DOW SILICONES CORPORATION (US) | 2019-04-04 | — | — | WO | claimed |
| EP-3081560-A1 | TAXANES COMPOUNDS, PREPARATION METHOD THEREFOR, AND USES THEREOF | Jiangsu Tasly Diyi Pharmaceutical Co., Ltd. (CN) | 2016-10-19 | — | — | EP | claimed |
| US-20160297784-A1 | Taxanes Compounds, Preparation Method Therefor, and Uses Thereof | JIANGSU TASLY DIYI PHARMACEUTICAL CO., LTD. (CN) | 2016-10-13 | — | — | US | claimed |
| WO-2006007917-A1 | COMPOSITION OF FLUORINATED SILICONES, PARTICULARLY BUT NOT EXCLUSIVELY FOR ADHESIVE-RELEASING COATINGS, AND PREPARATION THEREOF | MAFLON S.R.L. (IT) | 2006-01-26 | — | — | WO | claimed |
| JP-6211890-A | — | — | None | — | — | JP | disclosed |
| CN-115925675-B | PSAMMAPLIN A derivatives, and preparation method and application thereof | 中国海洋大学 | 2025-04-01 | — | — | CN | disclosed |
| CN-115925675-A | Psamaplin A derivative and preparation method and application thereof | 中国海洋大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-110997683-B | Synthesis of 1, 1-trichlorosilane | 南大光电半导体材料有限公司 | 2023-03-31 | — | — | CN | disclosed |
| WO-2021108198-A1 | INHIBITORS OF RECEPTOR INTERACTING PROTEIN KINASE I FOR THE TREATMENT OF DISEASE | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-06-03 | — | — | WO | disclosed |
| EP-3081560-B1 | TAXANES COMPOUNDS, PREPARATION METHOD THEREFOR, AND USES THEREOF | JIANGSU TASLY DIYI PHARMACEUTICAL CO LTD (CN) | 2021-03-24 | — | — | EP | disclosed |
| EP-0346427-A1 | MACROCYCLIC COMPOUNDS. | FISONS PLC (GB) | 1989-12-20 | — | — | EP | disclosed |
| EP-0323042-A1 | Process to macrocyclic compounds | FISONS plc (GB) | 1989-07-05 | — | — | EP | disclosed |
| WO-1989005304-A1 | MACROCYCLIC COMPOUNDS | FISONS PLC (GB) | 1989-06-15 | — | — | WO | disclosed |
| EP-0294229-A2 | Novel heterocyclic pesticidal compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1988-12-07 | — | — | EP | disclosed |
| EP-0073451-A2 | Carbapenam compound and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-03-09 | — | — | EP | disclosed |
| EP-0001715-A2 | Azetidinone antibiotics and their pharmaceutical formulations and use | ELI LILLY AND COMPANY (US) | 1979-05-02 | — | — | EP | disclosed |