Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Butane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL28863388 | 1.00 | TSHR (0.44) | — | |
| Butane SCHEMBL465278 | 1.00 | — | — | |
| Butane SCHEMBL4362011 | 1.00 | TSHR (0.44) | — | |
| Butane SCHEMBL27927071 | 1.00 | TSHR (0.44) | — | |
| Butane SCHEMBL5851369 | 1.00 | — | — | |
| Butane SCHEMBL18039280 | 1.00 | — | — | |
| Butane SCHEMBL12504128 | 0.93 | — | — | |
| Butane SCHEMBL3109038 | 0.93 | — | — | |
| Butane SCHEMBL10400622 | 0.93 | TSHR (0.40) | — | |
| Butane SCHEMBL2860854 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116022805-B | Small-grain ZSM-12 molecular sieve and preparation method thereof | 中国石油化工股份有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119751197-A | Method for preparing chlorinated hydrocarbon based on alcohol chloride product | 恒光新材料(江苏)股份有限公司 | 2025-04-04 | — | — | CN | claimed |
| CN-117603159-A | Thiadiazole compound containing hindered phenol group, preparation method thereof and application thereof in field of lubricating oil additives | 大连理工大学盘锦产业技术研究院 | 2024-02-27 | — | — | CN | claimed |
| WO-2024007505-A1 | CYCLOOLEFIN POLYMER FILM WITH OPTICAL ANISOTROPY AND PREPARATION METHOD THEREFOR | 广东新华粤石化集团股份公司 | 2024-01-11 | — | — | WO | claimed |
| CN-117039088-A | Three-dimensional pore gradient carbon nanofiber electrode for eutectic solvent flow battery and preparation method thereof | 江苏大学 | 2023-11-10 | — | — | CN | claimed |
| CN-116920494-A | Totally-enclosed caprolactam solvent exchange rotary pressure filter | 天华化工机械及自动化研究设计院有限公司 | 2023-10-24 | — | — | CN | claimed |
| CN-116354861-A | Sn-based organic-inorganic hybrid phase change material and preparation method and application thereof | 东南大学 | 2023-06-30 | — | — | CN | claimed |
| CN-116022805-A | Small-grain ZSM-12 molecular sieve and preparation method thereof | 中国石油化工股份有限公司 | 2023-04-28 | — | — | CN | claimed |
| CN-116022803-A | Silicon-aluminum MCM-47 molecular sieve and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-04-28 | — | — | CN | claimed |
| CN-113659150-A | Composite dual-functional electrode for eutectic solvent electrolyte flow battery | 江苏大学 | 2021-11-16 | — | — | CN | claimed |
| CN-110684050-B | Preparation method and application of 7-position vinyl substituted osmium heteropentadiyne | 厦门大学 | 2021-04-20 | — | — | CN | claimed |
| CN-109761982-B | 12N-substituted carbamoyl matrine derivative and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2020-05-01 | — | — | CN | claimed |
| CN-109761982-A | 12N- replaces amine formyl matrine derivative and its preparation method and application | 中国医学科学院医药生物技术研究所 | 2019-05-17 | — | — | CN | claimed |
| CN-108383841-A | A kind of preparation method of L-084 intermediate and its raw material | 山东科兴生物制品有限公司 | 2018-08-10 | — | — | CN | claimed |
| CN-104557573-B | The preparation method of (1S) 4,5 dimethoxy 1 [(methylamino) methyl] benzocyclobutane hydrochloride | 上海天慈生物谷生物工程有限公司 | 2018-02-27 | — | — | CN | claimed |
| CN-107345021-A | A kind of special LLDPE compositions of silanes crosslinked cable and preparation method thereof | 中国石化扬子石油化工有限公司 | 2017-11-14 | — | — | CN | claimed |
| US-8058345-B2 | Curable adhesive compositions containing reactive multi-functional acrylate | ILLINOIS TOOL WORKS INC. (US) | 2011-11-15 | — | — | US | claimed |
| US-6465649-B1 | Methods for the dealkylation of phosphonate esters | GILEAD SCIENCES, INC. | 2002-10-15 | — | — | US | claimed |
| CN-122079737-A | Method for synthesizing chloro-n-butane by using methallyl chloride byproduct HCl | — | 2026-05-26 | — | — | CN | disclosed |
| US-3946088-A | ALUMINUM CHLORIDE OR BROMIDE CATALYST, HYDROGEN CHLORIDE OR BROMIDE SOLVENT | EXXON RESEARCH & ENGINEERING CO. (US) | 1976-03-23 | — | — | US | disclosed |