Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 12/20 | 0.66 |
| ▸ | PDE3A | Q14432 | 12/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | PDE5A | O76074 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | PTAFR | P25105 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | BLM | P54132 | 1/20 | 0.66 |
| ▸ | PDE1A | P54750 | 1/20 | 0.66 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.66 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7800144 | 0.86 | PDE3B (0.75) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL11319201 | 0.81 | PDE3B (0.73) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL7804071 | 0.80 | PDE3B (0.72) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| Cilostamide SCHEMBL49742 | 0.80 | PDE3B (1.00) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL11317158 | 0.80 | PDE3B (1.00) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| Cilostamide SCHEMBL29491047 | 0.80 | PDE3B (1.00) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL7803147 | 0.79 | PDE3B (0.60) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL11322854 | 0.79 | PDE3B (0.81) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL11324828 | 0.79 | PDE3B (0.81) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL8780057 | 0.79 | PDE3B (0.55) | PDE3BPDE3AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57014574-A | — | — | None | — | — | JP | disclosed |
| JP-S5714574-A | CARBOSTYRIL DERIVATIVE | OTSUKA PHARMACEUT CO LTD | 1982-01-25 | — | — | JP | disclosed |