Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11275519 | 0.89 | ALDH1A1 (0.50) | MEN1KMT2APOLBHDAC3HDAC4 | |
| SCHEMBL11276667 | 0.89 | PRSS1 (0.45) | PPARAMEN1KMT2APOLBBLM | |
| SCHEMBL11278162 | 0.88 | NPC1 (0.51) | MEN1KMT2APOLBCTDSP1HDAC3 | |
| SCHEMBL11283331 | 0.87 | KMT2A (0.52) | MEN1KMT2APOLBCTDSP1HDAC1 | |
| SCHEMBL15455405 | 0.85 | PRSS1 (0.52) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL11285274 | 0.83 | KMT2A (0.53) | MEN1KMT2APOLBHDAC1GAA | |
| SCHEMBL11284845 | 0.83 | PPARA (0.58) | PPARAMEN1KMT2APOLBBLM | |
| SCHEMBL14838825 | 0.77 | PRSS1 (0.48) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL19129557 | 0.77 | KMT2A (0.46) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL17325084 | 0.77 | PRSS1 (0.48) | MEN1KMT2AHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309441-A | HYPOTENSIVE AGENTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-01-05 | — | — | US | disclosed |