Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM2 | P50570 | 8/20 | 0.71 |
| ▸ | MERTK | Q12866 | 4/20 | 0.56 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.56 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 3/20 | 0.48 |
| ▸ | TYRO3 | Q06418 | 3/20 | 0.48 |
| ▸ | GAS6 | Q14393 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | AXL | P30530 | 2/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11289519 | 0.94 | DNM2 (0.71) | DNM2MERTKNUDT1TLR8MAPK8 | |
| SCHEMBL1401613 | 0.91 | DNM2 (0.78) | DNM2MERTKNUDT1TLR8MAPK8 | |
| SCHEMBL19477219 | 0.86 | DNM2 (0.71) | DNM2MERTKNUDT1TLR8MAPK8 | |
| SCHEMBL28661902 | 0.80 | DNM2 (0.64) | DNM2MERTKNUDT1TLR8MAPK8 | |
| SCHEMBL19476566 | 0.80 | DNM2 (0.80) | DNM2MERTKTLR8MAPK8HRH4 | |
| SCHEMBL19477221 | 0.80 | DNM2 (0.80) | DNM2MERTKTLR8MAPK8HRH4 | |
| SCHEMBL19477222 | 0.79 | TLR8 (0.63) | DNM2MERTKNUDT1TLR8MAPK8 | |
| SCHEMBL19476564 | 0.79 | TLR8 (0.63) | DNM2MERTKNUDT1TLR8MAPK8 | |
| SCHEMBL11090421 | 0.79 | DNM2 (0.58) | DNM2MERTKTLR8MAPK8FLT3 | |
| SCHEMBL19706932 | 0.79 | DNM2 (0.62) | DNM2MERTKTLR8MAPK8HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339453-A | BACTERICIDES, FUNGICIDES | MERCK & CO., INC. (US) | 1982-07-13 | — | — | US | disclosed |