Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 10/20 | 0.78 |
| ▸ | PGR | P06401 | 2/20 | 0.78 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.78 |
| ▸ | LMNA | P02545 | 2/20 | 0.78 |
| ▸ | AR | P10275 | 1/20 | 0.78 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.78 |
| ▸ | NR3C1 | P04150 | 8/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.75 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.75 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.75 |
| ▸ | MAPT | P10636 | 2/20 | 0.75 |
| ▸ | SHBG | P04278 | 1/20 | 0.75 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.75 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11144452 | 1.00 | HIF1A (0.78) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL12235695 | 1.00 | HIF1A (0.78) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL332584 | 1.00 | HIF1A (0.78) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL2803362 | 0.93 | HIF1A (0.78) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL4618329 | 0.90 | HIF1A (0.84) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL14867487 | 0.90 | HIF1A (0.84) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL13368121 | 0.90 | HIF1A (0.84) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL9073513 | 0.88 | HIF1A (0.71) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL12396664 | 0.88 | HIF1A (0.71) | HIF1APGRSERPINA6LMNAAR | |
| Hydrocortisone Acetate SCHEMBL4940901 | 0.88 | HIF1A (1.00) | HIF1APGRSERPINA6LMNAAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0061416-A1 | Process for the preparation of Delta 9(11)- and delta 16-21-chloro-20-keto steroids of the pregnane and D-homopregnane series and their use as intermediates for the synthesis of highly effective corticoids | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-09-29 | — | — | EP | disclosed |