Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 10/20 | 0.84 |
| ▸ | PGR | P06401 | 2/20 | 0.84 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.84 |
| ▸ | LMNA | P02545 | 2/20 | 0.84 |
| ▸ | AR | P10275 | 1/20 | 0.84 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.84 |
| ▸ | NR3C1 | P04150 | 8/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.82 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.82 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.82 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.82 |
| ▸ | MAPT | P10636 | 2/20 | 0.82 |
| ▸ | SHBG | P04278 | 1/20 | 0.82 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.82 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.75 |
| ▸ | TSHR | P16473 | 1/20 | 0.75 |
| ▸ | POLB | P06746 | 1/20 | 0.74 |
| ▸ | GAA | P10253 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13368121 | 1.00 | HIF1A (0.84) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL14867487 | 0.94 | HIF1A (0.84) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL10940291 | 0.94 | HIF1A (0.84) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL10944869 | 0.94 | HIF1A (0.84) | HIF1APGRSERPINA6LMNAAR | |
| Hydrocortisone Acetate SCHEMBL7419 | 0.92 | HIF1A (1.00) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL21186498 | 0.92 | HIF1A (0.80) | HIF1APGRSERPINA6LMNAAR | |
| Hydrocortisone Acetate SCHEMBL4940901 | 0.92 | HIF1A (1.00) | HIF1APGRSERPINA6LMNAAR | |
| Hydrocortisone Acetate SCHEMBL13026148 | 0.92 | HIF1A (1.00) | HIF1APGRSERPINA6LMNAAR | |
| SCHEMBL3999010 | 0.92 | HIF1A (0.86) | HIF1APGRSERPINA6LMNAAR | |
| Hydrocortisone Acetate SCHEMBL2452043 | 0.92 | HIF1A (1.00) | HIF1APGRSERPINA6LMNAAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3604322-B1 | LACTULOSE GLYCOSIDE COMPOUND AND PREPARATION METHOD AND USE THEREOF | FRUITHY HOLDINGS LTD (CN) | 2023-10-18 | — | — | EP | disclosed |
| EP-3604322-A1 | LACTULOSE GLYCOSIDE COMPOUND AND PREPARATION METHOD AND USE THEREOF | FRUITHY HOLDINGS LIMITED (CN) | 2020-02-05 | — | — | EP | disclosed |
| US-9809817-B2 | Oligonucleotide compounds for targeting huntingtin mRNA | UNIVERSITY OF MASSACHUSETTS (US) | 2017-11-07 | — | — | US | disclosed |
| US-20160355808-A1 | OLIGONUCLEOTIDE COMPOUNDS FOR TARGETING HUNTINGTIN mRNA | UNIVERSITY OF MASSACHUSETTS | 2016-12-08 | — | — | US | disclosed |
| US-20160355826-A1 | OLIGONUCLEOTIDE COMPOUNDS FOR TREATMENT OF PREECLAMPSIA AND OTHER ANGIOGENIC DISORDERS | UNIVERSITY OF MASSACHUSETTS | 2016-12-08 | — | — | US | disclosed |
| WO-2014087323-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF AUTOIMMUNE AND CHRONIC METABOLIC DISEASES | KANDULA MAHESH (IN) | 2014-06-12 | — | — | WO | disclosed |
| US-8486374-B2 | Alcohol-free drug or cosmetics carrier mixture of water, hydrophobic solvent, surfactant and gelling agent; oil in water emulsions | FOAMIX LTD. (IL) | 2013-07-16 | — | — | US | disclosed |
| US-20080299220-A1 | HYDROPHILIC, NON-AQUEOUS PHARMACEUTICAL CARRIERS AND COMPOSITIONS AND USES | VYNE THERAPEUTICS INC. (F/K/A MENLO THERAPEUTICS INC. AND SUCCESSOR-IN-INTEREST TO VYNE PHARMACEUTICALS LTD., F/K/A FOAMIX PHARMACEUTICALS LTD.) | 2008-12-04 | — | — | US | disclosed |
| US-20080292560-A1 | SILICONE IN GLYCOL PHARMACEUTICAL AND COSMETIC COMPOSITIONS WITH ACCOMMODATING AGENT | FOAMIX PHARMACEUTICALS LTD. (IL) | 2008-11-27 | — | — | US | disclosed |
| US-20080206161-A1 | QUIESCENT FOAMABLE COMPOSITIONS, STEROIDS, KITS AND USES THEREOF | FOAMIX PHARMACEUTICALS LTD. (IL) | 2008-08-28 | — | — | US | disclosed |
| US-20080063607-A1 | Oleaginous pharmaceutical and cosmetic foam | FOAMIX LTD | 2008-03-13 | — | — | US | disclosed |
| EP-1890679-A2 | STEROID KIT AND FOAMABLE COMPOSITION AND USES THEREOF | Foamix Ltd. (IL) | 2008-02-27 | — | — | EP | disclosed |
| US-20070292461-A1 | Oleaginous pharmaceutical and cosmetic foam | FOAMIX LTD. (IL) | 2007-12-20 | — | — | US | disclosed |
| WO-2007012977-A2 | STEROID KIT AND FOAMABLE COMPOSITION AND USES THEREOF | FOAMIX LTD (US) | 2007-02-01 | — | — | WO | disclosed |
| US-20060018937-A1 | Steroid kit and foamable composition and uses thereof | FOAMIX LTD. | 2006-01-26 | — | — | US | disclosed |
| EP-0607088-B1 | New 17,20-epoxy pregnane derivatives, their use in the preparation of cortisone derivatives and intermediates therefor | ROUSSEL UCLAF (FR) | 1997-04-09 | — | — | EP | disclosed |
| EP-0607088-A1 | New 17,20-epoxy pregnane derivatives, their use in the preparation of cortisone derivatives and intermediates therefor | ROUSSEL UCLAF (FR) | 1994-07-20 | — | — | EP | disclosed |
| US-3956349-A | TRIETHYL ORTHOACETATE, ACID CATALYST | SYNTEX (U.S.A.) INC. (US) | 1976-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080206161-A1 | QUIESCENT FOAMABLE COMPOSITIONS, STEROIDS, KITS AND USES THEREOF | NR5A1, CYP17A1, LIPA | HIF1A 941/4885PGR 129/4885SERPINA6 14/4885 |
| US-20160355808-A1 | OLIGONUCLEOTIDE COMPOUNDS FOR TARGETING HUNTINGTIN mRNA | HTT, HYPK, RNMT | HIF1A 3715/4885PGR 4559/4885SERPINA6 1168/4885 |
| US-20080292560-A1 | SILICONE IN GLYCOL PHARMACEUTICAL AND COSMETIC COMPOSITIONS WITH ACCOMMODATING AGENT | SSTR2, SSTR3, LPXN | HIF1A 2486/4885PGR 53/4885SERPINA6 754/4885 |
| US-20070292461-A1 | Oleaginous pharmaceutical and cosmetic foam | LIPA, LIPC, PLIN3 | HIF1A 3511/4885PGR 301/4885SERPINA6 1937/4885 |
| US-20080063607-A1 | Oleaginous pharmaceutical and cosmetic foam | LIPA, LIPC, PLIN3 | HIF1A 3511/4885PGR 301/4885SERPINA6 1937/4885 |
| US-20160355826-A1 | OLIGONUCLEOTIDE COMPOUNDS FOR TREATMENT OF PREECLAMPSIA AND OTHER ANGIOGENIC DISORDERS | FLT4, VEGFA, PGF | HIF1A 287/4885PGR 2707/4885SERPINA6 92/4885 |
| US-20080299220-A1 | HYDROPHILIC, NON-AQUEOUS PHARMACEUTICAL CARRIERS AND COMPOSITIONS AND USES | LIPA, PHOSPHO1, MYO1G | HIF1A 3632/4885PGR 11/4885SERPINA6 877/4885 |
| US-20060018937-A1 | Steroid kit and foamable composition and uses thereof | KIT, GK, HSD17B7 | HIF1A 894/4885PGR 114/4885SERPINA6 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.