Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3482710 | 0.87 | — | — | |
| SCHEMBL9746214 | 0.87 | — | — | |
| SCHEMBL10818644 | 0.83 | MEN1 (0.50) | MEN1CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL10890710 | 0.83 | MEN1 (0.50) | MEN1CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL24268905 | 0.79 | — | — | |
| SCHEMBL3482522 | 0.71 | MEN1 (0.36) | MEN1CYP1A2CYP3A4CYP2D6TSHR | |
| Oxalic Acid SCHEMBL11330545 | 0.69 | MEN1 (0.39) | MEN1CYP1A2CYP3A4CYP2D6TSHR | |
| Sulfuric Acid SCHEMBL11325182 | 0.69 | MEN1 (0.39) | MEN1CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL24584655 | 0.69 | MEN1 (0.44) | MEN1CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL24584563 | 0.69 | MEN1 (0.44) | MEN1CYP1A2CYP3A4CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359425-A | OF A DIAMONO FUSED SATURATED HYDROCARBON RING, HAVING ANTITUMOR ACTIVITY | SHIONOGI & CO., LTD. (JP) | 1982-11-16 | — | — | US | claimed |
| US-4359425-A | OF A DIAMONO FUSED SATURATED HYDROCARBON RING, HAVING ANTITUMOR ACTIVITY | SHIONOGI & CO., LTD. (JP) | 1982-11-16 | — | — | US | disclosed |