⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9674229 | 0.80 | — | — | |
| SCHEMBL8351504 | 0.76 | — | — | |
| SCHEMBL11284075 | 0.75 | TET2 (0.48) | — | |
| SCHEMBL11290372 | 0.73 | ALDH1A1 (0.35) | — | |
| SCHEMBL11180525 | 0.72 | ALDH1A1 (0.34) | — | |
| SCHEMBL10470968 | 0.70 | GAA (0.50) | — | |
| SCHEMBL12727665 | 0.69 | GAA (0.52) | — | |
| SCHEMBL1324567 | 0.69 | — | — | |
| SCHEMBL5025144 | 0.67 | — | — | |
| SCHEMBL21199817 | 0.67 | KMT2A (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4365062-A | BACTERICIDAL ANTIBIOTICS | RHONE-POULENC INDUSTRIES (FR) | 1982-12-21 | — | — | US | disclosed |
| US-4307233-A | ANTIBACTERIAL AGENTS | RHONE-POULENC INDUSTRIES (FR) | 1981-12-22 | — | — | US | disclosed |
| US-4307230-A | ANTIBIOTICS | RHONE-POULENC INDUSTRIES (FR) | 1981-12-22 | — | — | US | disclosed |
| US-4307116-A | BACTERICIDES | RHONE-POULENC INDUSTRIES (FR) | 1981-12-22 | — | — | US | disclosed |