Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 3/20 | 0.37 |
| ▸ | CES1 | P23141 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10630308 | 1.00 | ALOX5 (0.55) | ALOX5ALDH1A1TSHRKDM4ECYP1A2 | |
| SCHEMBL17779527 | 0.84 | ALOX5 (0.59) | ALOX5ALDH1A1TSHRKDM4ECYP1A2 | |
| SCHEMBL11213402 | 0.84 | ALOX5 (0.59) | ALOX5ALDH1A1TSHRKDM4ECYP1A2 | |
| SCHEMBL417928 | 0.84 | ALOX5 (0.59) | ALOX5ALDH1A1TSHRKDM4ECYP1A2 | |
| SCHEMBL301664 | 0.84 | ALOX5 (0.59) | ALOX5ALDH1A1TSHRKDM4ECYP1A2 | |
| SCHEMBL24354392 | 0.84 | ALOX5 (0.59) | ALOX5ALDH1A1TSHRKDM4ECYP1A2 | |
| SCHEMBL15177351 | 0.84 | ALOX5 (0.55) | ALOX5ALDH1A1TSHRKDM4ECYP1A2 | |
| SCHEMBL11414522 | 0.84 | ALOX5 (0.59) | ALOX5ALDH1A1TSHRKDM4ECYP1A2 | |
| SCHEMBL21972780 | 0.84 | ALOX5 (0.59) | ALOX5ALDH1A1TSHRKDM4ECYP1A2 | |
| SCHEMBL3491458 | 0.84 | ALOX5 (0.59) | ALOX5ALDH1A1TSHRKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |