Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 7/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.58 |
| ▸ | F12 | P00748 | 3/20 | 0.58 |
| ▸ | F10 | P00742 | 2/20 | 0.58 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.58 |
| ▸ | MLNR | O43193 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | C1R | P00736 | 1/20 | 0.58 |
| ▸ | PLG | P00747 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.58 |
| ▸ | HPN | P05981 | 1/20 | 0.58 |
| ▸ | KLK1 | P06870 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.58 |
| ▸ | C1S | P09871 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7343610 | 0.92 | FTO (0.64) | F2PRSS1F12F10ST14 | |
| SCHEMBL8756332 | 0.86 | MAPT (0.60) | MAPTALDH1A1LMNASLC6A3PARP10 | |
| SCHEMBL7337750 | 0.86 | F12 (0.71) | F2PRSS1F12F10ST14 | |
| SCHEMBL19430636 | 0.86 | F2 (0.74) | F2PRSS1F10ST14PLAU | |
| Hydrochloric Acid SCHEMBL7830226 | 0.85 | F2 (0.76) | F2PRSS1F10ST14PLAU | |
| SCHEMBL31380450 | 0.82 | F12 (0.76) | F2PRSS1F12F10ST14 | |
| SCHEMBL7345716 | 0.82 | PLAU (0.53) | F2PRSS1F12F10ST14 | |
| SCHEMBL7338848 | 0.81 | F12 (0.71) | F2PRSS1F12F10ST14 | |
| SCHEMBL7343617 | 0.80 | PLAU (0.50) | F2PRSS1F10ST14ITGB3 | |
| SCHEMBL20008714 | 0.80 | PRSS1 (0.63) | F2PRSS1F12F10ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048433-A2 | Novel amidine compounds, process for producing same and anti-complement agent comprising them | TORII & CO., LTD. (JP) | 1982-03-31 | — | — | EP | disclosed |