SCHEMBL1128329

SCHEMBL1128329

N#CC1(C#N)CO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17185661 0.65
SCHEMBL2047747 0.50
SCHEMBL18322215 0.50 ALDH1A1 (0.35)
SCHEMBL8579390 0.50
SCHEMBL18322224 0.50 ALDH1A1 (0.35)
SCHEMBL4563750 0.49
SCHEMBL18823089 0.49 NPC1 (0.37)
SCHEMBL29210790 0.46
SCHEMBL11382309 0.46
Water SCHEMBL28598887 0.45

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2283019-A1 GPR119 RECEPTOR AGONISTS F. Hoffmann-La Roche AG (CH) 2011-02-16 EP disclosed
WO-2009141238-A1 GPR119 RECEPTOR AGONISTS F. HOFFMANN-LA ROCHE AG (CH) 2009-11-26 WO disclosed
EP-1741811-B1 Fiber containing an antimicrobial composition ROHM & HAAS (US) 2007-08-22 EP disclosed
EP-0166652-B1 PROCESS FOR THE RING OPENING OF GEM-DICYANOEPOXIDES, AND COMPOUNDS OBTAINED BY THIS PROCESS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1990-04-25 EP disclosed
US-4786744-A REACTION WITH ALCOHOL OR AMINE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1988-11-22 US disclosed
EP-0166650-B1 PROCESS FOR OPENING THE RING OF GEM-DICYANOEPOXYDES AND COMPOUNDS PRODUCED BY THIS PROCESS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1988-03-16 EP disclosed