Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16207199 | 0.86 | TSHR (0.35) | TSHR | |
| SCHEMBL18391716 | 0.84 | MAPT (0.32) | TSHR | |
| SCHEMBL11283293 | 0.84 | MAPT (0.32) | TSHR | |
| SCHEMBL25688662 | 0.84 | MAPT (0.32) | TSHR | |
| SCHEMBL18683565 | 0.84 | MAPT (0.32) | TSHR | |
| SCHEMBL17538638 | 0.84 | MAPT (0.32) | TSHR | |
| SCHEMBL9276620 | 0.84 | MAPT (0.32) | TSHR | |
| SCHEMBL4544647 | 0.84 | MAPT (0.32) | TSHR | |
| SCHEMBL21628145 | 0.84 | MAPT (0.32) | TSHR | |
| SCHEMBL30156363 | 0.84 | TSHR (0.33) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063368-A1 | Process for the preparation of pregn-4-ene-3,20-dione derivatives and 17-alpha-ethynyl-17-beta-trifluoroacetoxy-gon-4-ene-3-one derivatives, and pharmaceutical compositions containing the latter compounds | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1982-10-27 | — | — | EP | disclosed |