SCHEMBL4544647

SCHEMBL4544647

OC1CCC2C(CCC3C4CCCC4CCC23)C1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.32
CA12 O43570 2/20 0.32
GMNN O75496 2/20 0.32
ALDH1A1 P00352 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
LMNA P02545 2/20 0.32
BLM P54132 2/20 0.32
CA9 Q16790 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
SGMS1 Q86VZ5 1/20 0.32
SGMS2 Q8NHU3 1/20 0.32
CTDSP1 Q9GZU7 2/20 0.32
KDM4E B2RXH2 2/20 0.32
MEN1 O00255 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18683555 1.00 MAPT (0.32) MAPTCA12GMNNALDH1A1CA1
SCHEMBL18391716 1.00 MAPT (0.32) MAPTCA12GMNNALDH1A1CA1
SCHEMBL28257150 1.00 MAPT (0.32) MAPTCA12GMNNALDH1A1CA1
SCHEMBL25688662 1.00 MAPT (0.32) MAPTCA12GMNNALDH1A1CA1
SCHEMBL11283293 1.00 MAPT (0.32) MAPTCA12GMNNALDH1A1CA1
SCHEMBL17538638 1.00 MAPT (0.32) MAPTCA12GMNNALDH1A1CA1
SCHEMBL18683565 1.00 MAPT (0.32) MAPTCA12GMNNALDH1A1CA1
SCHEMBL30156363 0.95 TSHR (0.33) MAPTCA12GMNNALDH1A1CA1
SCHEMBL16207199 0.93 TSHR (0.35) ALDH1A1TSHR
Ethylene Glycol SCHEMBL28177955 0.92 CYP1A2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240216515-A1 COMPOSITIONS AND METHODS FOR TARGETED DELIVERY TO CELLS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2024-07-04 US disclosed
US-20240216515-A1 COMPOSITIONS AND METHODS FOR TARGETED DELIVERY TO CELLS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2024-07-04 US disclosed
US-20240216290-A1 LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF RECODE THERAPEUTICS, INC. 2024-07-04 US disclosed
US-20240216290-A1 LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF RECODE THERAPEUTICS, INC. 2024-07-04 US disclosed
US-12024486-B2 Lipocationic dendrimers and uses thereof THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-07-02 US disclosed
US-12024486-B2 Lipocationic dendrimers and uses thereof THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-07-02 US disclosed
US-20240207178-A1 COMPOSITIONS AND METHODS FOR TARGETED DELIVERY TO CELLS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2024-06-27 US disclosed
EP-4358936-A1 NUCLEIC ACID CONTAINING NANOPARTICLES Bio-TRIP B.V. (NL) 2024-05-01 EP disclosed
WO-2024073588-A1 RESPIRATORY DRY POWDER DELIVERY BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-04-04 WO disclosed
CN-117545467-A Nucleic acid-containing nanoparticles 比奥-特里普公司 2024-02-09 CN disclosed
WO-2011089595-A2 SUSTAINED-RELEASE NUCLEIC ACID MATRIX COMPOSITIONS POLYPID LTD. (IL) 2011-07-28 WO disclosed
US-20110117197-A1 SUSTAINED-RELEASE DRUG CARRIER COMPOSITION POLYPID LTD. (IL) 2011-05-19 US disclosed
US-20110117197-A1 SUSTAINED-RELEASE DRUG CARRIER COMPOSITION POLYPID LTD. (IL) 2011-05-19 US disclosed
WO-2011007353-A1 SUSTAINED-RELEASE DRUG CARRIER COMPOSITION POLYPID LTD. (IL) 2011-01-20 WO disclosed
WO-2010113157-A1 LIPOPEPTIDE INHIBITORS OF HIV-1 YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2010-10-07 WO disclosed
US-20100093682-A1 LIPID COMPOSITION HAVING EXCELLENT SHAPE RETENTION PROPERTY AND PRODUCT TAKASAGO INTERNATIONAL CORPORATION (JP) 2010-04-15 US disclosed
US-20100093682-A1 LIPID COMPOSITION HAVING EXCELLENT SHAPE RETENTION PROPERTY AND PRODUCT TAKASAGO INTERNATIONAL CORPORATION (JP) 2010-04-15 US disclosed
WO-2009082607-A2 TARGETING LIPIDS ALNYLAM PHARMACEUTICALS, INC. (US) 2009-07-02 WO disclosed
EP-1448069-B1 DETERIORATION PREVENTIVE AGENT TAKASAGO PERFUMERY CO LTD (JP) 2009-06-03 EP disclosed
US-7342004-B2 Thioether sulphamate steroids as steroid inhibitors and anti-cancer compounds STERIX LTD. (GB) 2008-03-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100093682-A1 LIPID COMPOSITION HAVING EXCELLENT SHAPE RETENTION PROPERTY AND PRODUCT MGLL, LIPC, CETP MAPT 63/4885CA12 3139/4885GMNN 2117/4885
US-12024486-B2 Lipocationic dendrimers and uses thereof LIPA, LIPC, TLR9 MAPT 3510/4885CA12 3983/4885GMNN 945/4885
US-20240207178-A1 COMPOSITIONS AND METHODS FOR TARGETED DELIVERY TO CELLS CHMP4B, LIPA, NPC1L1 MAPT 1993/4885CA12 986/4885GMNN 2103/4885
US-20110117197-A1 SUSTAINED-RELEASE DRUG CARRIER COMPOSITION LIPA, LIPC, ABCB11 MAPT 3001/4885CA12 2319/4885GMNN 1786/4885
US-20240216290-A1 LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF LIPA, NPC1L1, NPC1 MAPT 1927/4885CA12 2178/4885GMNN 1426/4885
US-20240216515-A1 COMPOSITIONS AND METHODS FOR TARGETED DELIVERY TO CELLS PNLIP, LIPA, PHOSPHO1 MAPT 2479/4885CA12 1787/4885GMNN 1834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.