SCHEMBL11283703

SCHEMBL11283703

OC(Cc1ccccc1)[C@H]1O[CH][C@](O)(Cc2ccccc2)[C@@]1(O)Cc1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
ADRA1D P25100 1/20 0.33
ADRA1A P35348 1/20 0.33
ADRA1B P35368 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2A Q12879 1/20 0.33
GRIN2B Q13224 1/20 0.33
GRIN2C Q14957 1/20 0.33
GRIN3A Q8TCU5 1/20 0.33
TRPA1 O75762 2/20 0.32
CYP1A2 P05177 1/20 0.32
OPRM1 P35372 2/20 0.31
OPRD1 P41143 2/20 0.31
OPRK1 P41145 2/20 0.31
OPRL1 P41146 2/20 0.31
EPHX1 P07099 1/20 0.31
ALPL P05186 1/20 0.30
POLB P06746 1/20 0.30
ALPG P10696 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4024047 1.00 GRIN2D (0.33) GRIN2DGRIN3BADRA1DADRA1AADRA1B
SCHEMBL8583373 0.90 GRIN2D (0.31) GRIN2DGRIN3BADRA1DADRA1AADRA1B
SCHEMBL3136547 0.77 GRIN2D (0.33) GRIN2DGRIN3BADRA1DADRA1AADRA1B
SCHEMBL3155159 0.77 GRIN2D (0.33) GRIN2DGRIN3BADRA1DADRA1AADRA1B
SCHEMBL3145397 0.77 GRIN2D (0.33) GRIN2DGRIN3BADRA1DADRA1AADRA1B
SCHEMBL3163944 0.77 GRIN2D (0.33) GRIN2DGRIN3BADRA1DADRA1AADRA1B
SCHEMBL31016265 0.77 GRIN2D (0.33) GRIN2DGRIN3BADRA1DADRA1AADRA1B
SCHEMBL11124714 0.75 GRIN2D (0.32) GRIN2DGRIN3BADRA1DADRA1AADRA1B
SCHEMBL6637475 0.75 GRIN2D (0.32) GRIN2DGRIN3BADRA1DADRA1AADRA1B
SCHEMBL4024044 0.75 CYP1A2 (0.34) GRIN2DGRIN3BADRA1DADRA1AADRA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0043722-A1 Beta-D-Arabinofuranosylimidazo (4,5-c)pyridine compounds and processes for their production WARNER-LAMBERT COMPANY (US) 1982-01-13 EP claimed