Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31016265 | 0.87 | GRIN2D (0.33) | GRIN2DGRIN3BADRA1DADRA1AADRA1B | |
| SCHEMBL3163944 | 0.87 | GRIN2D (0.33) | GRIN2DGRIN3BADRA1DADRA1AADRA1B | |
| SCHEMBL3136547 | 0.87 | GRIN2D (0.33) | GRIN2DGRIN3BADRA1DADRA1AADRA1B | |
| SCHEMBL3145397 | 0.87 | GRIN2D (0.33) | GRIN2DGRIN3BADRA1DADRA1AADRA1B | |
| SCHEMBL3155159 | 0.87 | GRIN2D (0.33) | GRIN2DGRIN3BADRA1DADRA1AADRA1B | |
| SCHEMBL4024044 | 0.83 | CYP1A2 (0.34) | GRIN2DGRIN3BADRA1DADRA1AADRA1B | |
| SCHEMBL11124714 | 0.83 | GRIN2D (0.32) | GRIN2DGRIN3BADRA1DADRA1AADRA1B | |
| SCHEMBL7645453 | 0.81 | TRPA1 (0.32) | TRPA1HTT | |
| SCHEMBL2045566 | 0.81 | GRIN2D (0.31) | GRIN2DGRIN3BADRA1DADRA1AADRA1B | |
| SCHEMBL2045564 | 0.81 | GRIN2D (0.31) | GRIN2DGRIN3BADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1418877-A2 | REAGENTS THAT FACILITATE THE PURIFICATION OF COMPOUNDS SYNTHESIZED ON A SOLID SUPPORT | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2004-05-19 | — | — | EP | disclosed |
| WO-2003017930-A2 | REAGENTS THAT FACILITATE THE PURIFICATION OF COMPOUNDS SYNTHESIZED ON A SOLID SUPPORT | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2003-03-06 | — | — | WO | disclosed |