Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 3/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2830764 | 0.94 | TSHR (0.43) | TSHRHPGDZDHHC20ZDHHC2THRB | |
| SCHEMBL14956997 | 0.92 | TSHR (0.42) | TSHRHPGDZDHHC20ZDHHC2THRB | |
| SCHEMBL1235391 | 0.89 | TSHR (0.42) | TSHRHPGDZDHHC20ZDHHC2THRB | |
| SCHEMBL8415194 | 0.89 | TSHR (0.42) | TSHRHPGDZDHHC20ZDHHC2THRB | |
| SCHEMBL11279407 | 0.89 | TSHR (0.42) | TSHRHPGDZDHHC20ZDHHC2THRB | |
| SCHEMBL8827503 | 0.87 | TSHR (0.38) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL11281825 | 0.86 | TSHR (0.42) | TSHRHPGDZDHHC20ZDHHC2THRB | |
| SCHEMBL499683 | 0.83 | TSHR (0.42) | TSHRHPGDZDHHC20ZDHHC2THRB | |
| SCHEMBL500591 | 0.83 | TSHR (0.42) | TSHRHPGDZDHHC20ZDHHC2THRB | |
| SCHEMBL499596 | 0.83 | TSHR (0.42) | TSHRHPGDZDHHC20ZDHHC2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0047009-A1 | Hydrophilic interpolymers of acrylic acid and an olefin or a styrene | The B.F. GOODRICH Company (US) | 1982-03-10 | — | — | EP | disclosed |