SCHEMBL499683

SCHEMBL499683

C=CC(=O)OC(CCCCCCC)N(CC)CC

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.42
HPGD P15428 1/20 0.42
THRB P10828 2/20 0.40
THRA P10827 1/20 0.40
ZDHHC20 Q5W0Z9 2/20 0.37
ZDHHC2 Q9UIJ5 2/20 0.37
GPR84 Q9NQS5 5/20 0.36
FFAR1 O14842 1/20 0.36
ZDHHC7 Q9NXF8 1/20 0.36
MAPT P10636 1/20 0.35
LCK P06239 1/20 0.35
PPARD Q03181 1/20 0.35
HCAR2 Q8TDS4 1/20 0.35
FAAH O00519 1/20 0.35
ABCB1 P08183 1/20 0.35
ALDH1A1 P00352 1/20 0.34
CYP3A4 P08684 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL499596 1.00 TSHR (0.42) TSHRHPGDTHRBTHRAZDHHC20
SCHEMBL11674285 1.00 TSHR (0.42) TSHRHPGDTHRBTHRAZDHHC20
SCHEMBL500591 1.00 TSHR (0.42) TSHRHPGDTHRBTHRAZDHHC20
SCHEMBL11521548 0.98 TSHR (0.43) TSHRHPGDTHRBTHRAZDHHC20
SCHEMBL8993527 0.94 TSHR (0.47) TSHRHPGDTHRBTHRAZDHHC20
SCHEMBL11281825 0.88 TSHR (0.42) TSHRHPGDTHRBTHRAZDHHC20
SCHEMBL14956997 0.88 TSHR (0.42) TSHRHPGDTHRBTHRAZDHHC20
SCHEMBL11279407 0.88 TSHR (0.42) TSHRHPGDTHRBTHRAZDHHC20
SCHEMBL927084 0.87 TSHR (0.39) TSHRHPGDTHRBTHRAALDH1A1
SCHEMBL499747 0.86 TSHR (0.43) TSHRHPGDTHRBTHRAZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5321110-A Thickeners for shampoo, hair conditioners ISP INVESTMENTS INC. (US) 1994-06-14 US claimed
EP-0106193-A2 Liquid skin cleanser composition UNION CARBIDE CORPORATION (US) 1984-04-25 EP claimed
US-3954960-A Hair and similar cosmetic preparations containing a quaternized copolymer of vinyl pyrrolidone GAF CORPORATION (US) 1976-05-04 US claimed
EP-3347446-B1 A STABLE LAUNDRY OR CLEANING COMPOSITION, PROCESS FOR PREPARING THE SAME, AND METHOD OF USE ISP INVESTMENTS LLC (US) 2024-12-11 EP disclosed
US-12096767-B2 Residual disinfectant composition KIMBERLY-CLARK WORLDWIDE, INC. (US) 2024-09-24 US disclosed
US-20230277704-A1 Disinfectant Composition with Rapid Antiviral Efficacy KIMBERLY-CLARK WORLDWIDE, INC. 2023-09-07 US disclosed
EP-3328373-B1 DISINFECTANT COMPOSITION WITH RAPID ANTIVIRAL EFFICACY KIMBERLY CLARK CO (US) 2023-06-07 EP disclosed
EP-3569682-B1 LIQUID HARD SURFACE CLEANING COMPOSITIONS HAVING IMPROVED VISCOSITY PROCTER & GAMBLE (US) 2022-12-07 EP disclosed
WO-2022162221-A1 DETERGENT COMPOSITION UNILEVER IP HOLDINGS B.V. (NL) 2022-08-04 WO disclosed
US-11384316-B2 Stable laundry cleaning composition and method comprising a polyAPTAC-containing polymer ISP INVESTMENTS LLC (US) 2022-07-12 US disclosed
US-10995302-B2 Liquid acidic hard surface cleaning compositions having improved viscosity THE PROCTER & GAMBLE COMPANY (US) 2021-05-04 US disclosed
US-6063368-A MIXTURE OF FOAMING AGENT, WATER SOLUBLE FILM FORMING QUATERNIZED POLYMER AND WATER AVEDA CORPORATION (US) 2000-05-16 US disclosed
US-5321110-A Thickeners for shampoo, hair conditioners ISP INVESTMENTS INC. (US) 1994-06-14 US disclosed
US-5045617-A Zwitterion terpolymers of a vinyl lactam, an amino alkyl acrylamide or acrylate, and a polymerizable carboxylic acid ISP INVESTMENTS INC. (US) 1991-09-03 US disclosed
US-4465802-A WITH WATER SOLUBLE CATIONIC POLYMER AND CATIONIC SURFACTANT UNION CARBIDE CORPORATION (US) 1984-08-14 US disclosed
US-4362528-A OXIDATION COLOR DYE,CATIONIC POLYMER TO IMPROVE FEEL,SHAMPOO WITH ANIONIC DETERGENT SOCIETE ANONYME DITE: L'OREAL (FR) 1982-12-07 US disclosed
US-4314807-A CATIONIC POLYMER, ANIONIC SURFACTANT SHAMPOO L'OREAL (FR) 1982-02-09 US disclosed
US-3980769-A ANIONIC AND AMPHOTERIC SURFACTANTS L'OREAL (FR) 1976-09-14 US disclosed
US-3958581-A Cosmetic composition containing a cationic polymer and divalent metal salt for strengthening the hair L'OREAL (FR) 1976-05-25 US disclosed
US-3954960-A Hair and similar cosmetic preparations containing a quaternized copolymer of vinyl pyrrolidone GAF CORPORATION (US) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12096767-B2 Residual disinfectant composition QARS1, EIF2AK2, POLL TSHR 2755/4885HPGD 4715/4885THRB 4598/4885
US-20230277704-A1 Disinfectant Composition with Rapid Antiviral Efficacy EIF2AK2, APOBEC3A, APOBEC3C TSHR 2150/4885HPGD 2149/4885THRB 4223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.