Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11257786 | 0.80 | CYP3A4 (0.47) | CHRNB2CHRNA4APPDRD2DRD4 | |
| SCHEMBL11257782 | 0.80 | CYP3A4 (0.47) | CHRNB2CHRNA4APPDRD2DRD4 | |
| SCHEMBL2727598 | 0.79 | CHRNB2 (0.50) | CHRNB2CHRNA4APPDRD2DRD4 | |
| SCHEMBL11286590 | 0.78 | CHRNB2 (0.47) | CHRNB2CHRNA4APPDRD2DRD4 | |
| SCHEMBL11265947 | 0.76 | CYP3A4 (0.50) | CHRNB2CHRNA4APPDRD2DRD4 | |
| SCHEMBL11265951 | 0.76 | CYP3A4 (0.50) | CHRNB2CHRNA4APPDRD2DRD4 | |
| 3-(Allyloxy)Phenol SCHEMBL27494286 | 0.72 | APP (0.47) | CHRNB2CHRNA4APPCHRNB4CHRNA3 | |
| 3-(Allyloxy)Phenol SCHEMBL483058 | 0.72 | APP (0.50) | CHRNB2CHRNA4APPDRD2DRD4 | |
| SCHEMBL4414589 | 0.70 | CHRNB2 (0.56) | CHRNB2CHRNA4APPDRD2DRD4 | |
| 3-(Allyloxy)Phenol SCHEMBL27721429 | 0.70 | APP (0.49) | CHRNB2CHRNA4APPDRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046283-A2 | 4-Phenoxy-2-butene derivatives and their use as plant growth regulators | J.T. Baker Chemical Co. (US) | 1982-02-24 | — | — | EP | disclosed |