Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.52 |
| ▸ | AKT1 | P31749 | 2/20 | 0.47 |
| ▸ | APLNR | P35414 | 2/20 | 0.46 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | CALCR | P30988 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11284539 | 1.00 | OPRM1 (0.52) | OPRM1OPRD1AKT1APLNREPHA2 | |
| SCHEMBL29934618 | 0.83 | OPRM1 (0.51) | OPRM1OPRD1APLNR | |
| SCHEMBL31596986 | 0.83 | OPRM1 (0.64) | OPRM1OPRD1 | |
| SCHEMBL31596868 | 0.83 | OPRM1 (0.64) | OPRM1OPRD1 | |
| SCHEMBL31612385 | 0.82 | OPRM1 (0.61) | OPRM1OPRD1 | |
| SCHEMBL30495505 | 0.81 | OPRM1 (0.54) | OPRM1OPRD1AKT1EPHA2 | |
| SCHEMBL30377344 | 0.79 | CALCRL (0.54) | APLNREPHA2CALCR | |
| SCHEMBL30376895 | 0.79 | CALCRL (0.54) | APLNREPHA2CALCR | |
| SCHEMBL30475332 | 0.79 | OPRM1 (0.59) | OPRM1OPRD1 | |
| SCHEMBL29743002 | 0.79 | CALCRL (0.44) | OPRM1OPRD1CALCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4351828-A | N-Substituted cyclopeptide derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-09-28 | — | — | US | disclosed |
| US-4237045-A | N-substituted cyclopeptide derivatives and preparation thereof | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-12-02 | — | — | US | disclosed |