Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dimethyl Sulfoxide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethyl Sulfoxide SCHEMBL8608347 | 1.00 | — | — | |
| Dimethyl Sulfoxide SCHEMBL9236588 | 0.96 | — | — | |
| Dimethyl Sulfoxide SCHEMBL6470105 | 0.96 | — | — | |
| SCHEMBL6667401 | 0.81 | — | — | |
| Butane SCHEMBL6004324 | 0.79 | ALDH1A1 (0.33) | — | |
| SCHEMBL1736341 | 0.78 | ALDH1A1 (0.40) | — | |
| SCHEMBL124190 | 0.78 | — | — | |
| SCHEMBL30 | 0.78 | — | — | |
| Butane SCHEMBL16013445 | 0.75 | PLA2G1B (0.31) | — | |
| SCHEMBL28165349 | 0.75 | MEN1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112120995-A | Anti-wrinkle gel mask and preparation method thereof | 南京飞天一淼科技服务有限公司 | 2020-12-25 | — | — | CN | claimed |
| CN-106831584-B | A kind of efficient method for preparing tri- substituted pyrazolecarboxylic class compound of 1,3,5- | 江西师范大学 | 2019-11-22 | — | — | CN | claimed |
| CN-106467563-B | The synthetic method and its midbody compound of chondroitin sulfate tetrose | 北京大学 | 2019-08-06 | — | — | CN | claimed |
| CN-106467563-A | The synthetic method of chondroitin sulfate tetrose and its midbody compound | 北京大学 | 2017-03-01 | — | — | CN | claimed |
| US-4978744-A | Synthesis of dolastatin 10 | ARIZONA BOARD OF REGENTS (US) | 1990-12-18 | — | — | US | claimed |
| CN-112120995-B | Anti-wrinkle gel mask and preparation method thereof | 佛山市百分之秀化妆品有限公司 | 2024-07-23 | — | — | CN | disclosed |
| CN-116948228-A | Copper-containing nano enzyme composite film and preparation method thereof | 中国石油大学(华东) | 2023-10-27 | — | — | CN | disclosed |
| WO-2023158584-A1 | NEW BICYCLOPENTANE DERIVATIVES | ICAGEN, LLC (US) | 2023-08-24 | — | — | WO | disclosed |
| CN-113952985-A | Method for efficiently preparing high-performance MOF-based non-noble metal monatomic composite material under assistance of microwaves, composite material and application | 中国科学技术大学 | 2022-01-21 | — | — | CN | disclosed |
| CN-112120995-A | Anti-wrinkle gel mask and preparation method thereof | 南京飞天一淼科技服务有限公司 | 2020-12-25 | — | — | CN | disclosed |
| CN-112120995-A | Anti-wrinkle gel mask and preparation method thereof | 南京飞天一淼科技服务有限公司 | 2020-12-25 | — | — | CN | disclosed |
| CN-111905108-A | Nano-drug system for targeted therapy of liver cancer and preparation method thereof | 北京医院 | 2020-11-10 | — | — | CN | disclosed |
| WO-2009131974-A1 | THIOPHENYL-SUBSTITUTED 2-IMINO-3-METHYL PYRROLO PYRIMIDINONE COMPOUNDS AS BACE-1 INHIBITORS, COMPOSITIONS, AND THEIR USE | SCHERING CORPORATION (US) | 2009-10-29 | — | — | WO | disclosed |
| EP-1979309-A2 | PROCESS FOR THE PREPARATION OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-A]IMIDAZOLE-3-SULFONIC ACID AMIDES AND INTERMEDIATES USED THEREIN | Boehringer Ingelheim International GmbH (DE) | 2008-10-15 | — | — | EP | disclosed |
| WO-2008119176-A1 | AMIDATION PROCESS FOR THE PREPARATION OF CATHEPSIN K INHIBITORS | MERCK FROSST CANADA LTD. (CA) | 2008-10-09 | — | — | WO | disclosed |
| WO-2007084882-A2 | PROCESS FOR THE PREPARATION OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-A]IMIDAZOLE-3-SULFONIC ACID AMIDES AND INTERMEDIATES USED THEREIN | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-07-26 | — | — | WO | disclosed |
| US-20070173517-A1 | Synthesis of 6,7-Dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonic acid amides | WIRTH THOMAS | 2007-07-26 | — | — | US | disclosed |
| WO-2002056991-A2 | SYSTEMS AND METHODS FOR PERFORMING ELECTROKINETIC CHROMATOGRAPHY | ARQULE, INC. (US) | 2002-07-25 | — | — | WO | disclosed |
| US-5021439-A | Senile dementia and memory dysfunction | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-06-04 | — | — | US | disclosed |
| US-4978744-A | Synthesis of dolastatin 10 | ARIZONA BOARD OF REGENTS (US) | 1990-12-18 | — | — | US | disclosed |