Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.67 |
| ▸ | NPC1 | O15118 | 7/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | TP53 | P04637 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | HTT | P42858 | 4/20 | 0.67 |
| ▸ | USP2 | O75604 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | EGFR | P00533 | 1/20 | 0.59 |
| ▸ | SRC | P12931 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25720090 | 0.86 | RAB9A (0.73) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL10674807 | 0.86 | MEN1 (0.58) | RAB9ANPC1ALDH1A1LMNAKDM4E | |
| SCHEMBL10675667 | 0.86 | RAB9A (0.67) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL15155052 | 0.83 | MEN1 (0.59) | RAB9ANPC1ALDH1A1LMNAKDM4E | |
| SCHEMBL25720375 | 0.80 | RAB9A (1.00) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL10673248 | 0.78 | KDM4E (0.64) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL25720132 | 0.77 | MEN1 (0.61) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL8998908 | 0.74 | SRC (1.00) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL2660935 | 0.73 | EGFR (0.76) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL25720093 | 0.73 | MEN1 (0.56) | RAB9ANPC1ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0059698-A1 | Heterocyclic carboxamides, compositions containing such compounds, processes for their preparation and methods of treatment therewith | AB LEO (SE) | 1982-09-08 | — | — | EP | disclosed |