Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.55 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.55 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11015972 | 0.90 | TDP1 (0.59) | TDP1CTDSP1MAPK1MAPTPOLB | |
| SCHEMBL9642504 | 0.90 | TDP1 (0.59) | TDP1CTDSP1MAPK1MAPTPOLB | |
| SCHEMBL27275320 | 0.90 | TDP1 (0.59) | TDP1CTDSP1MAPK1MAPTPOLB | |
| SCHEMBL10579475 | 0.90 | TDP1 (0.59) | TDP1CTDSP1MAPK1MAPTPOLB | |
| SCHEMBL7804219 | 0.90 | TDP1 (0.59) | TDP1CTDSP1MAPK1MAPTPOLB | |
| SCHEMBL1132359 | 0.90 | TDP1 (0.59) | TDP1CTDSP1MAPK1MAPTPOLB | |
| SCHEMBL9099692 | 0.90 | TDP1 (0.59) | TDP1CTDSP1MAPK1MAPTPOLB | |
| SCHEMBL9699338 | 0.89 | TDP1 (0.58) | TDP1CTDSP1MAPK1MAPTPOLB | |
| SCHEMBL11690600 | 0.89 | TDP1 (0.58) | TDP1CTDSP1MAPK1MAPTPOLB | |
| SCHEMBL9766170 | 0.89 | TDP1 (0.58) | TDP1CTDSP1MAPK1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4365062-A | BACTERICIDAL ANTIBIOTICS | RHONE-POULENC INDUSTRIES (FR) | 1982-12-21 | — | — | US | claimed |
| US-4365062-A | BACTERICIDAL ANTIBIOTICS | RHONE-POULENC INDUSTRIES (FR) | 1982-12-21 | — | — | US | disclosed |