Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.59 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.55 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.55 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11015972 | 1.00 | TDP1 (0.59) | TDP1CTDSP1MAPK1MAPTPOLB | |
| SCHEMBL9099692 | 1.00 | TDP1 (0.59) | TDP1CTDSP1MAPK1MAPTPOLB | |
| SCHEMBL10579475 | 1.00 | TDP1 (0.59) | TDP1CTDSP1MAPK1MAPTPOLB | |
| SCHEMBL27275320 | 1.00 | TDP1 (0.59) | TDP1CTDSP1MAPK1MAPTPOLB | |
| SCHEMBL9642504 | 1.00 | TDP1 (0.59) | TDP1CTDSP1MAPK1MAPTPOLB | |
| SCHEMBL1132359 | 1.00 | TDP1 (0.59) | TDP1CTDSP1MAPK1MAPTPOLB | |
| SCHEMBL14065427 | 0.94 | TDP1 (0.61) | TDP1CTDSP1MAPK1MAPTPOLB | |
| SCHEMBL8849392 | 0.93 | TDP1 (0.57) | TDP1CTDSP1MAPK1MAPTPOLB | |
| SCHEMBL9699338 | 0.92 | TDP1 (0.58) | TDP1CTDSP1MAPK1MAPTPOLB | |
| SCHEMBL11690596 | 0.92 | TDP1 (0.58) | TDP1CTDSP1MAPK1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503453-B1 | New process for the production of cephalosporines and novel intermediates in this process | BIOCHEMIE GMBH (AT) | 2001-05-09 | — | — | EP | disclosed |
| US-5401841-A | Process for the production of cephalosporines | SANDOZ LTD. (CH) | 1995-03-28 | — | — | US | disclosed |
| US-5171854-A | Antibiotics | BAYER AKTIENGESELLSCHAFT (DE) | 1992-12-15 | — | — | US | disclosed |
| EP-0503453-A2 | New process for the production of cephalosporines and novel intermediates in this process | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 1992-09-16 | — | — | EP | disclosed |
| EP-0121244-B1 | CEPHALOSPORIN DERIVATIVES | Bristol-Myers Company (US) | 1990-09-12 | — | — | EP | disclosed |
| EP-0103264-B1 | NEW CEPHEM COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-12-20 | — | — | EP | disclosed |
| EP-0097961-B1 | CEPHALOSPORIN DERIVATIVES, A PROCESS FOR THE MANUFACTURE THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | Bristol-Myers Company (US) | 1987-11-11 | — | — | EP | disclosed |
| US-4639448-A | 7-amino-3-[substituted vinyl]-3-cephem-4-carboxylates having antimicrobial activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-01-27 | — | — | US | disclosed |
| US-4546101-A | CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-10-08 | — | — | US | disclosed |
| US-4537720-A | N-substituted-2-(R)-(sulfinic acid)-3-(S)-(acylamino)-4-oxo-azetidines and process | ELI LILLY AND COMPANY (US) | 1985-08-27 | — | — | US | disclosed |
| US-4493833-A | BACTERICIDES, ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-01-15 | — | — | US | disclosed |
| EP-0121244-A2 | Cephalosporin derivatives | Bristol-Myers Company (US) | 1984-10-10 | — | — | EP | disclosed |
| EP-0109816-A1 | N-substituted-2-(R)-(sulfinic acid)-3-(S)-(acylamido)-4-oxo-azetidines and process | ELI LILLY AND COMPANY (US) | 1984-05-30 | — | — | EP | disclosed |
| EP-0103264-A2 | New cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-21 | — | — | EP | disclosed |
| US-4436596-A | N-Substituted-2-(R)-(sulfinic acid)-3-(S)-(acylamido)-4-oxo-azetidines and process | ELI LILLY AND COMPANY (US) | 1984-03-13 | — | — | US | disclosed |
| EP-0097961-A2 | Cephalosporin derivatives, a process for the manufacture thereof and pharmaceutical compositions containing said derivatives | Bristol-Myers Company (US) | 1984-01-11 | — | — | EP | disclosed |
| US-4304770-A | Syn-isomer of 3,7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-12-08 | — | — | US | disclosed |