Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11285492 | 1.00 | TSHR (0.32) | TSHRSMN1; SMN2DNM1ALDH1A1 | |
| SCHEMBL11282169 | 0.93 | LCK (0.36) | DNM1 | |
| SCHEMBL11282173 | 0.93 | LCK (0.36) | DNM1 | |
| SCHEMBL11288921 | 0.91 | LCK (0.39) | TSHRDNM1 | |
| SCHEMBL11288917 | 0.91 | LCK (0.39) | TSHRDNM1 | |
| SCHEMBL11275598 | 0.86 | — | — | |
| SCHEMBL11275586 | 0.86 | — | — | |
| SCHEMBL11277223 | 0.83 | DNM1 (0.39) | TSHRSMN1; SMN2DNM1ALDH1A1 | |
| SCHEMBL11277225 | 0.83 | DNM1 (0.39) | TSHRSMN1; SMN2DNM1ALDH1A1 | |
| SCHEMBL11278430 | 0.80 | MEN1 (0.44) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000555-B1 | PROCESS FOR THE PREPARATION OF OXIRANES SUBSTITUTED BY HALOGEN ALKYL | BAYER AG (DE) | 1982-02-10 | — | — | EP | disclosed |
| EP-0000554-B1 | PROCESS FOR THE PREPARATION OF OXIRANES SUBSTITUTED BY HALOGEN ALKYL | BAYER AG (DE) | 1982-02-10 | — | — | EP | disclosed |
| EP-0000554-A1 | Process for the preparation of oxiranes substituted by halogen alkyl | BAYER AG (DE) | 1979-02-07 | — | — | EP | disclosed |