Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 13/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.42 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11196452 | 1.00 | ACE (0.51) | ACENPC1RAB9ASMN1; SMN2HTR2C | |
| SCHEMBL4435031 | 0.89 | ACE (0.61) | ACENPC1RAB9ASMN1; SMN2CACNA1G | |
| SCHEMBL7270216 | 0.89 | ACE (0.61) | ACENPC1RAB9ASMN1; SMN2CACNA1G | |
| SCHEMBL7271397 | 0.88 | ACE (0.57) | ACENPC1RAB9ASMN1; SMN2HTR2C | |
| SCHEMBL7271391 | 0.88 | ACE (0.57) | ACENPC1RAB9ASMN1; SMN2HTR2C | |
| SCHEMBL15134208 | 0.87 | ACE (0.48) | ACENPC1RAB9ASMN1; SMN2HTR2C | |
| SCHEMBL28405346 | 0.87 | ACE (0.48) | ACENPC1RAB9ASMN1; SMN2HTR2C | |
| SCHEMBL7264075 | 0.85 | ACE (0.53) | ACENPC1RAB9ASMN1; SMN2HTR2C | |
| SCHEMBL7264101 | 0.85 | ACE (0.53) | ACENPC1RAB9ASMN1; SMN2HTR2C | |
| SCHEMBL1448040 | 0.81 | HTR2C (0.47) | ACENPC1RAB9ASMN1; SMN2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0052696-A1 | Novel 2-oxoimidazolidine derivative, a process for preparing same and a pharmaceutical composition containing the 2-oxoimidazolidine derivative | Tanabe Seiyaku Co., Ltd. (JP) | 1982-06-02 | — | — | EP | disclosed |