Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 11/20 | 0.61 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.48 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.48 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4435031 | 1.00 | ACE (0.61) | ACECACNA1GCACNA1HCACNA1IFKBP1A | |
| SCHEMBL11196452 | 0.89 | ACE (0.51) | ACECACNA1GCACNA1HCACNA1INPC1 | |
| SCHEMBL11285685 | 0.89 | ACE (0.51) | ACECACNA1GCACNA1HCACNA1INPC1 | |
| SCHEMBL7271397 | 0.84 | ACE (0.57) | ACEFKBP1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7271391 | 0.84 | ACE (0.57) | ACEFKBP1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15134208 | 0.83 | ACE (0.48) | ACENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28405346 | 0.83 | ACE (0.48) | ACENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7264075 | 0.83 | ACE (0.53) | ACENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7264101 | 0.83 | ACE (0.53) | ACENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1448040 | 0.80 | HTR2C (0.47) | ACEFKBP1ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0095163-A2 | 2-Oxo-imidazolidine compounds, a process for preparing the same and a pharmaceutical composition | Tanabe Seiyaku Co., Ltd. (JP) | 1983-11-30 | — | — | EP | disclosed |