Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.58 |
| ▸ | HNF4A | P41235 | 1/20 | 0.58 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.51 |
| ▸ | LCK | P06239 | 3/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | NQO2 | P16083 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11286011 | 1.00 | PTPN1 (0.58) | PTPN1HNF4ABACE1ESR2TUBB1 | |
| SCHEMBL9622274 | 0.89 | LCK (0.61) | PTPN1BACE1ESR2LCKPTPN2 | |
| SCHEMBL9622273 | 0.89 | LCK (0.61) | PTPN1BACE1ESR2LCKPTPN2 | |
| SCHEMBL27388811 | 0.84 | TUBB1 (0.56) | PTPN1HNF4ATUBB1LCKTRPA1 | |
| SCHEMBL5692806 | 0.82 | BACE1 (0.56) | PTPN1HNF4ABACE1PTPN2PTPN6 | |
| SCHEMBL5692808 | 0.82 | BACE1 (0.56) | PTPN1HNF4ABACE1PTPN2PTPN6 | |
| SCHEMBL10712182 | 0.81 | CHAT (0.58) | PTPN1HNF4ARELA | |
| SCHEMBL10712185 | 0.81 | CHAT (0.58) | PTPN1HNF4ARELA | |
| SCHEMBL19036493 | 0.81 | CHAT (0.58) | PTPN1HNF4ARELA | |
| (E)-3,4-Stilbendiol SCHEMBL1821396 | 0.81 | LCK (0.77) | PTPN1HNF4ABACE1TUBB1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049126-A1 | Alpha-methyl-benzyl-chlorophenols and process for their preparation | COALITE GROUP LIMITED (GB) | 1982-04-07 | — | — | EP | claimed |
| EP-0049126-A1 | Alpha-methyl-benzyl-chlorophenols and process for their preparation | COALITE GROUP LIMITED (GB) | 1982-04-07 | — | — | EP | disclosed |
| US-3954936-A | COPPER, COBALT, MANGANESE, NICKEL | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-05-04 | — | — | US | disclosed |