Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.61 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.61 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.61 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.61 |
| ▸ | HMOX1 | P09601 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11274893 | 0.92 | CYP2A6 (0.55) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL11281514 | 0.87 | CYP11B1 (0.50) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL11280663 | 0.87 | CYP11B1 (0.50) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL11273140 | 0.84 | CYP11B1 (0.52) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL11280089 | 0.80 | ALDH1A1 (0.47) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL11639842 | 0.80 | CYP19A1 (0.55) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL10551726 | 0.80 | CYP11B1 (0.51) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL10759280 | 0.79 | ALDH1A1 (0.62) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL10550847 | 0.78 | CYP11B1 (0.56) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL11643711 | 0.78 | CYP19A1 (0.52) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064244-A1 | Spermicidal 1-bis(arylalkyl)alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-11-10 | — | — | EP | disclosed |